Structure
STX3451 Biochemical
STX3451
Purity
>98% (HPLC)
Synonyms
STX3451; STX-3451; STX 3451; STX3451 biochemical
Purity/Purification
>98% (HPLC)
Target
Microtubule/Tubulin
Receptor
Microtubule/Tubulin
Chemical Name
2-(3-Bromo-4, 5-dimethoxybenzyl)-7-methoxy-6-sulfamoyloxy-1, 2, 3, 4-tetrahydroisoquinoline
Molecular Formula
C19H23BrN2O6S
CAS Number
1623785-58-9
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for STX3451 biochemical
A non-steroidal sulphamate analogue of 2-methoxyoestradiol (2ME2) and microtubule disruptor, shows anti-proliferative activity against NCI 60 cell lines with mean GI50 of 50nM; induces apoptosis in human malignant peripheral nerve sheath tumour (MPNST) cell lines, inhibits both PI3 kinase and mTOR signalling pathways, selectively kills MPNST-derived cells, but also halts growth of other tumour-derived NF1 cell lines.
Product Categories/Family for STX3451 biochemical
References
1. Shen YC, et al. Br J Cancer. 2015 Oct 20; 113 (8):1158-67.
2. Dohle W, et al. ChemMedChem. 2014 Aug; 9 (8):1783-93.
2. Dohle W, et al. ChemMedChem. 2014 Aug; 9 (8):1783-93.
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Product Notes
The STX3451 (Catalog #AAA3602399) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "STX3451, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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