Rabbit anti-Human PHLDA1 Polyclonal Antibody | anti-PHLDA1 antibody

PHLDA1 Rabbit pAb

Cat. Num. AAA4756837

• Gene Names: PHLDA1; PHRIP; TDAG51; DT1P1B11
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
• Purity: Affinity purified
• Synonyms: PHLDA1; Polyclonal Antibody; PHLDA1 Rabbit pAb; Pleckstrin homology-like domain family A member 1; anti-PHLDA1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level).
• Purity/Purification: Affinity purified
• Form/Format: Supplied in 50nM Tris-Glycine(pH7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

• Applicable Applications for anti-PHLDA1 antibody: Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunohistochemistry-Frozen (IHC-F), Immunocytochemistry (ICC), Immunofluorescence (IF)
• Application Notes: WB: 1:2000-1:10,000; IHC: 1:20; ICC/IF: 1:50
• Immunogen: A synthetic peptide of human PHLDA1
• Conjugation: Unconjugated
• Modification: Unmodified
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot detection of PHLDA1 in A375 cell lysates using PHLDA1 Rabbit pAb(1:1000 diluted).Predicted band size:45kDa.Observed band size:45kDa.)

Related Product Information for anti-PHLDA1 antibody

Pleckstrin homology-like domain family A member 1

Product Categories/Family for anti-PHLDA1 antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 83977459
• NCBI GeneID: 22822
• NCBI Accession #: NP_031376.3
• NCBI GenBank Nucleotide #: NM_007350.3
• UniProt Accession #: Q8WV24; Q15184; Q2TAN2; Q9NZ17; A1A4G9
• Molecular Weight: 45,016 Da
• NCBI Official Full Name: pleckstrin homology-like domain family A member 1
• NCBI Official Synonym Full Names: pleckstrin homology-like domain, family A, member 1
• NCBI Official Symbol: PHLDA1
• NCBI Official Synonym Symbols: PHRIP; TDAG51; DT1P1B11
• NCBI Protein Information: pleckstrin homology-like domain family A member 1; PQR protein; PQ-rich protein; proline-histidine rich protein; proline- and glutamine-rich protein; proline- and histidine-rich protein; apoptosis-associated nuclear protein; T-cell death-associated gene 5
• UniProt Protein Name: Pleckstrin homology-like domain family A member 1
• Protein Family: Pleckstrin homology-like domain family
• UniProt Gene Name: PHLDA1
• UniProt Synonym Gene Names: PHRIP; TDAG51; PQ-rich protein; PQR protein
• UniProt Entry Name: PHLA1_HUMAN

NCBI Description

This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008]

Uniprot Description

PHLDA1: Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.

Protein type: Nucleolus; Apoptosis

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: nucleoplasm; cytoplasmic vesicle membrane; nucleolus; plasma membrane

Molecular Function: protein binding

Biological Process: apoptosis; positive regulation of apoptosis; forebrain neuron differentiation; FasL biosynthetic process