INPP5J blocking peptide
INPP5J Peptide - C-terminal region
Target Description: Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles (By similarity).
NCBI and Uniprot Product Information
Uniprot Description
PI5PA: Inositol 5-phosphatase, which converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4- phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate- binding proteins that are present at membranes ruffles. Belongs to the inositol 1,4,5-trisphosphate 5- phosphatase type II family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.3.56; Phosphatase (non-protein); Carbohydrate Metabolism - inositol phosphate
Chromosomal Location of Human Ortholog: 22q12.2
Cellular Component: ruffle; growth cone; cytoplasm; plasma membrane; dendritic shaft; cytosol
Molecular Function: inositol-polyphosphate 5-phosphatase activity; SH3 domain binding
Biological Process: inositol phosphate metabolic process; phospholipid metabolic process; negative regulation of microtubule polymerization; phosphatidylinositol biosynthetic process; negative regulation of peptidyl-serine phosphorylation; phosphoinositide dephosphorylation
Research Articles on INPP5J
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Product Notes
The INPP5J inpp5j (Catalog #AAA3247519) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The INPP5J Peptide - C-terminal region reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: Synthetic peptide located within the following region: TLELLAPKSR SPSPGKSKRH RSRSPGLARF PGLALRPSSR ERRGASRSPS. It is sometimes possible for the material contained within the vial of "INPP5J, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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