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Western Blot (WB) (Host: RabbitTarget Name: RND3Sample Type: NCI-H226 Whole Cell lysatesAntibody Dilution: 1.0ug/mlRND3 is supported by BioGPS gene expression data to be expressed in NCIH226)

Rabbit RND3 Polyclonal Antibody | anti-RND3 antibody

RND3 Antibody - C-terminal region

Gene Names
RND3; ARHE; Rho8; RhoE; memB
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Applications
Western Blot
Purity
Affinity Purified
Synonyms
RND3; Polyclonal Antibody; RND3 Antibody - C-terminal region; anti-RND3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: TLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKSCTV
Sequence Length
244
Applicable Applications for anti-RND3 antibody
Western Blot (WB)
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human RND3
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Host: RabbitTarget Name: RND3Sample Type: NCI-H226 Whole Cell lysatesAntibody Dilution: 1.0ug/mlRND3 is supported by BioGPS gene expression data to be expressed in NCIH226)

Western Blot (WB) (Host: RabbitTarget Name: RND3Sample Type: NCI-H226 Whole Cell lysatesAntibody Dilution: 1.0ug/mlRND3 is supported by BioGPS gene expression data to be expressed in NCIH226)
Related Product Information for anti-RND3 antibody
This is a rabbit polyclonal antibody against RND3. It was validated on Western Blot

Target Description: This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Product Categories/Family for anti-RND3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
390
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27kDa
NCBI Official Full Name
rho-related GTP-binding protein RhoE
NCBI Official Synonym Full Names
Rho family GTPase 3
NCBI Official Symbol
RND3
NCBI Official Synonym Symbols
ARHE; Rho8; RhoE; memB
NCBI Protein Information
rho-related GTP-binding protein RhoE
UniProt Protein Name
Rho-related GTP-binding protein RhoE
UniProt Gene Name
RND3
UniProt Synonym Gene Names
ARHE; RHO8; RHOE
UniProt Entry Name
RND3_HUMAN

NCBI Description

This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]

Uniprot Description

RhoE: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Binds ROCK1. Interacts with UBXD5. Ubiquitous. Belongs to the small GTPase superfamily. Rho family.

Protein type: G protein, monomeric; G protein, monomeric, Rho; G protein; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q23.3

Cellular Component: Golgi membrane; focal adhesion

Molecular Function: GTPase activity; protein binding; GTP binding

Biological Process: metabolic process; small GTPase mediated signal transduction; cell adhesion; actin cytoskeleton organization and biogenesis

Research Articles on RND3

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Product Notes

The RND3 rnd3 (Catalog #AAA3214694) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RND3 Antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's RND3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the RND3 rnd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: TLACVNKTNK NVKRNKSQRA TKRISHMPSR PELSAVATDL RKDKAKSCTV. It is sometimes possible for the material contained within the vial of "RND3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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