Rabbit LULL1/TOR1AIP2 Polyclonal Antibody | anti-LULL1/TOR1AIP2 antibody

LULL1/TOR1AIP2 Polyclonal Antibody

Cat. Num. AAA3015332

• Gene Names: TOR1AIP2; NET9; LULL1; IFRG15
• Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
• Applications: Western Blot, Immunohistochemistry
• Purity: affinity purified by Protein A
• Synonyms: LULL1/TOR1AIP2; Polyclonal Antibody; LULL1/TOR1AIP2 Polyclonal Antibody; TOR1AIP2; IFRG15; Interferon responsive gene 15; LULL1; Lumenal domain like LAP1; NET9; RP11-12M5.5; Torsin 1A interacting protein 2; Torsin A interacting protein 2.; anti-LULL1/TOR1AIP2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
• Clonality: Polyclonal
• Specificity: LULL1 Polyclonal Antibody detects endogenous levels of LULL1 protein.
• Purity/Purification: affinity purified by Protein A
• Form/Format: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Applicable Applications for anti-LULL1/TOR1AIP2 antibody: Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: WB: 1:500-2000; IHC-P: 1:100-500
• Immunogen: KLH conjugated synthetic peptide derived from human LULL1:221-320/470
• Preparation and Storage: Store at 4 degree C short term. Aliquot and store at -31 degree C long term. Avoid freeze-thaw cycles.

Testing Data

(Primary: Anti-LULL1/TOR1AIP2 at 1/300 dilution)

Testing Data

(Primary: Anti-LULL1/TOR1AIP2 at 1/300 dilution)

Testing Data

(Primary: Anti-LULL1/TOR1AIP2 at 1/1000 dilution)

Immunohistochemistry (IHC)

(Paraformaldehyde-fixed, paraffin embedded (mouse kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LULL1) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C)

Related Product Information for anti-LULL1/TOR1AIP2 antibody

LULL1 is a 470 amino acid endoplasmic reticulum single-pass membrane protein belonging to the TOR1AIP family. LULL1 interacts with torsinA, an essential AAA+ ATPase found in the endoplasmic reticulum (ER) and nuclear envelope (NE) of higher eukaryotes. LULL1 regulates the distribution and activity of torsinA within the ER and NE lumen and reveals functional defects in mutant torsinA, which is responsible for DYT1 dystonia, a neurodevelopmental disease caused by an in-frame deletion (Deltagag) in the gene encoding torsinA. The gene encoding LULL1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

NCBI and Uniprot Product Information

• NCBI GI #: 312922356
• NCBI GeneID: 163590
• NCBI Accession #: NP_001186189.1
• NCBI GenBank Nucleotide #: NM_001199260.1
• UniProt Accession #: Q8NFQ8; Q9H496
• Molecular Weight: 51,263 Da
• NCBI Official Full Name: torsin-1A-interacting protein 2 isoform b
• NCBI Official Synonym Full Names: torsin A interacting protein 2
• NCBI Official Symbol: TOR1AIP2
• NCBI Official Synonym Symbols: NET9; LULL1; IFRG15
• NCBI Protein Information: interferon alpha responsive protein; torsin-1A-interacting protein 2; lumenal domain like LAP1; lumenal domain-like LAP1; interferon responsive gene 15; 15 kDa interferon-responsive protein
• UniProt Protein Name: Torsin-1A-interacting protein 2
• UniProt Gene Name: TOR1AIP2
• UniProt Synonym Gene Names: IFRG15; LULL1
• UniProt Entry Name: TOIP2_HUMAN