Immunohistochemistry (IHC)
(Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SKOR2) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C)
Rabbit SKOR2 Polyclonal Antibody | anti-SKOR2 antibody
SKOR2 Polyclonal Antibody
Gene Names
SKOR2; CORL2; CH18515; FUSSEL18
Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep
Applications
Immunohistochemistry
Purity
affinity purified by Protein A
Synonyms
SKOR2; Polyclonal Antibody; SKOR2 Polyclonal Antibody; CORL2; Functional smad suppressing element 18; Functional Smad-suppressing element on chromosome 18; Fussel-18; FUSSEL18; Ladybird homeobox corepressor 1-like protein; LBX1 corepressor 1-like protein; SKI family transcriptional corepressor 2; SKOR2_HUMAN; anti-SKOR2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep
Clonality
Polyclonal
Specificity
SKOR2 Polyclonal Antibody detects endogenous levels of SKOR2 protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 54% Glycerol.
Applicable Applications for anti-SKOR2 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:100-500
Immunogen
KLH conjugated synthetic peptide derived from human SKOR2:871-970/100
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -27 degree C long term. Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SKOR2) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C)
Immunohistochemistry (IHC)
(Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SKOR2) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C)
Immunohistochemistry (IHC)
(Paraformaldehyde-fixed, paraffin embedded (rat spinal cord tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SKOR2) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C)
Immunohistochemistry (IHC)
(Paraformaldehyde-fixed, paraffin embedded (rat spinal cord tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SKOR2) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C)
Related Product Information for anti-SKOR2 antibody
The sloan kettering virus (Ski) family of nuclear oncoproteins act as transcriptional regulators of TGF-? by interacting directly with SMAD proteins. Fussel-18 (functional Smad-suppressing element on chromosome 18), also known as SKOR2 (Ski family transcriptional corepressor 2), LBX1 corepressor 1-like protein, ladybird homeobox corepressor 1-like protein or CORL2, is a 1,001 amino acid protein that belongs to the Ski family. Localizing to nucleus as well as cytoplasm, Fussel-18 is expressed in cerebellum, spinal cord and testis. Fussel-18 acts as an antagonist to TGF-? in the nervous system, possibly by functioning as a transcriptional repressor of SMAD2 and SMAD3. Existing as two alternatively spliced isoforms, the gene encoding Fussel-18 maps to human chromosome 18q21.1 and mouse chromosome 18 E3.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,354 Da
NCBI Official Full Name
SKI family transcriptional corepressor 2 isoform 2
NCBI Official Synonym Full Names
SKI family transcriptional corepressor 2
NCBI Official Symbol
SKOR2
NCBI Official Synonym Symbols
CORL2; CH18515; FUSSEL18
NCBI Protein Information
SKI family transcriptional corepressor 2
UniProt Protein Name
SKI family transcriptional corepressor 2
Protein Family
UniProt Gene Name
SKOR2
UniProt Synonym Gene Names
CORL2; FUSSEL18; Fussel-18
Uniprot Description
Exhibits transcriptional repressor activity (). Acts as a TGF-beta antagonist in the nervous system.
Research Articles on SKOR2
1. Experiments performed using mice, but the observations maybe relevant to other organisms as well.
Similar Products
Product Notes
The SKOR2 skor2 (Catalog #AAA3015336) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SKOR2 Polyclonal Antibody reacts with Human, Mouse, Rat, Dog, Cow, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's SKOR2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:100-500. Researchers should empirically determine the suitability of the SKOR2 skor2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SKOR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
