Western Blot (WB)
(Western Blot analysis of OS9 on mouse testis and rat testis tissue lysates using anti-OS9 antibody at 1/2,000 dilution.)
Rabbit OS9 Polyclonal Antibody | anti-OS9 antibody
OS9 Polyclonal Antibody
IHC: 1:50-1:200
IP: 1:10-1:50
Aliquot store at -20 degree C.
Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western Blot analysis of OS9 on mouse testis and rat testis tissue lysates using anti-OS9 antibody at 1/2,000 dilution.)
Western Blot (WB)
(Western Blot analysis of OS9 on mouse testis and rat testis tissue lysates using anti-OS9 antibody at 1/2,000 dilution.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-OS9 antibody. Counter stained with hematoxylin.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-OS9 antibody. Counter stained with hematoxylin.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Uniprot Description
OS9: Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4. Belongs to the OS-9 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: endoplasmic reticulum lumen
Molecular Function: protein binding; protease binding; glycoprotein binding; carbohydrate binding
Biological Process: ER-associated protein catabolic process; protein ubiquitination during ubiquitin-dependent protein catabolic process; protein ubiquitination; protein retention in ER; protein targeting
Research Articles on OS9
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Product Notes
The OS9 os9 (Catalog #AAA3013176) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The OS9 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's OS9 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP). WB: 1:500-1:2,000 IHC: 1:50-1:200 IP: 1:10-1:50. Researchers should empirically determine the suitability of the OS9 os9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OS9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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