Rabbit VTI1B Polyclonal Antibody | anti-VTI1B antibody

VTI1B Polyclonal Antibody

Cat. Num. AAA3007631

• Gene Names: VTI1B; VTI1; VTI2; VTI1L; v-SNARE; vti1-rp1; VTI1-LIKE
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: VTI1B; Polyclonal Antibody; VTI1B Polyclonal Antibody; Vesicle transport through interaction with t-SNAREs homolog 1B; Vesicle transport v-SNARE protein Vti1-like 1; Vti1-rp1; VTI1; VTI1L; VTI1L1; VTI2; anti-VTI1B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: VTI1B polyclonal antibody detects endogenous levels of VTI1B protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 232

• Applicable Applications for anti-VTI1B antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding to amino acids 50-100 of Human VTI1B.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of VTI1B polyclonal antibody at 1:500 dilutionLane1:MCF-7 whole cell lysate (40ug) Lane2:HepG2 whole cell lysate (40ug) Lane3:MEF whole cell lysate (40ug) Lane4:H9C2 whole cell lysate (40ug))

Related Product Information for anti-VTI1B antibody

Vesicle transport through interaction with t-SNAREs homolog 1B, V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.

NCBI and Uniprot Product Information

• NCBI GI #: 5454166
• NCBI GeneID: 10490
• NCBI Accession #: NP_006361.1
• NCBI GenBank Nucleotide #: NP_006361.1
• UniProt Accession #: Q9UEU0
• Molecular Weight: ~ 27kDa
• NCBI Official Full Name: vesicle transport through interaction with t-SNAREs homolog 1B
• NCBI Official Synonym Full Names: vesicle transport through interaction with t-SNAREs 1B
• NCBI Official Symbol: VTI1B
• NCBI Official Synonym Symbols: VTI1; VTI2; VTI1L; v-SNARE; vti1-rp1; VTI1-LIKE
• NCBI Protein Information: vesicle transport through interaction with t-SNAREs homolog 1B
• UniProt Protein Name: Vesicle transport through interaction with t-SNAREs homolog 1B
• Protein Family: Vesicle transport through interaction with t-SNAREs
• UniProt Gene Name: VTI1B
• UniProt Synonym Gene Names: VTI1; VTI1L; VTI1L1; VTI2
• UniProt Entry Name: VTI1B_HUMAN

Uniprot Description

VTI1B: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. Belongs to the VTI1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: SNARE complex; Golgi apparatus; endoplasmic reticulum membrane; recycling endosome; synaptic vesicle; cell soma; intracellular membrane-bound organelle; late endosome membrane; lysosomal membrane; perinuclear region of cytoplasm; cytoplasm; integral to membrane; vesicle

Molecular Function: SNAP receptor activity; SNARE binding; chloride channel inhibitor activity

Biological Process: vesicle-mediated transport; cell proliferation; intra-Golgi vesicle-mediated transport; ER to Golgi vesicle-mediated transport; autophagic vacuole fusion; Golgi to vacuole transport; vesicle fusion with Golgi apparatus; protein targeting to vacuole; retrograde transport, endosome to Golgi; vesicle docking during exocytosis