Western Blot (WB)
(Western Blot (WB) analysis of ZNF462 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysateLane2:PC12 whole cell lysate)
Rabbit anti-Human, Rat ZNF462 Polyclonal Antibody | anti-ZNF462 antibody
ZNF462 Polyclonal Antibody
Gene Names
ZNF462; WSKA; ZFPIP; Zfp462
Reactivity
Human, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
ZNF462; Polyclonal Antibody; ZNF462 Polyclonal Antibody; Zinc finger protein 462; KIAA1803; anti-ZNF462 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
ZNF462 polyclonal antibody detects endogenous levels of ZNF462 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
2506
Applicable Applications for anti-ZNF462 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human ZNF462.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of ZNF462 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysateLane2:PC12 whole cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of ZNF462 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysateLane2:PC12 whole cell lysate)
Related Product Information for anti-ZNF462 antibody
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF462 (zinc finger protein 462) is a 2, 506 amino acid protein that localizes to nucleus and is subject to posttranslational phosphorylation upon DNA damage, possibly by ATM or ATR.Containing twenty-seven C2H2-type zinc finger motifs and existing as multiple alternatively spliced isoforms, ZNF462 is encoded by a gene located on human chromosome 9q31.2. Chromosome 9 consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9.Notably, chromosome 9 encompasses the largest interferon family gene cluster.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 285kDa
NCBI Official Full Name
zinc finger protein 462 isoform 1
NCBI Official Synonym Full Names
zinc finger protein 462
NCBI Official Symbol
ZNF462
NCBI Official Synonym Symbols
WSKA; ZFPIP; Zfp462
NCBI Protein Information
zinc finger protein 462
UniProt Protein Name
Zinc finger protein 462
Protein Family
UniProt Gene Name
ZNF462
UniProt Synonym Gene Names
KIAA1803
UniProt Entry Name
ZN462_HUMAN
NCBI Description
The protein encoded by this gene belongs to C2H2-type zinc finger family of proteins. It contains multiple C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Research Articles on ZNF462
Similar Products
Product Notes
The ZNF462 znf462 (Catalog #AAA3007070) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZNF462 Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZNF462 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the ZNF462 znf462 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZNF462, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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