Typical Testing Data/Standard Curve (for reference only)
Human Stereocilin ELISA Kit | STRC elisa kit
Human Stereocilin ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is associated with the hair bundle of the sensory hair cells in the inner ear. The hair bundle is composed of stiff microvilli called stereocilia and is involved with mechanoreception of sound waves. This gene is part of a tandem duplication on chromosome 15; the second copy is a pseudogene. Mutations in this gene cause autosomal recessive non-syndromic deafness. [provided by RefSeq, Jul 2008]
Uniprot Description
STRC: Essential to the formation of horizontal top connectors between outer hair cell stereocilia. Defects in STRC are the cause of deafness autosomal recessive type 16 (DFNB16). DFNB16 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Defects in STRC are a cause of deafness-infertility syndrome (DIS). DIS is characterized by deafness and infertility and is caused by large contiguous gene deletions at 15q15.3 that removes both STRC and CATSPER2 genes. Belongs to the stereocilin family.
Chromosomal Location of Human Ortholog: 15q15.3
Cellular Component: cell surface; stereocilium bundle tip
Biological Process: auditory receptor cell stereocilium organization and biogenesis; cell-matrix adhesion; detection of mechanical stimulus involved in sensory perception of sound; sensory perception of sound
Disease: Deafness, Autosomal Recessive 16; Deafness, Sensorineural, And Male Infertility; Spermatogenic Failure 7
Research Articles on STRC
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Product Notes
The Human STRC strc (Catalog #AAA2886374) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886374 ELISA Kit recognizes Human STRC. It is sometimes possible for the material contained within the vial of "Stereocilin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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