Typical Testing Data/Standard Curve (for reference only)
Rat Heparin-binding growth factor 2 ELISA Kit | Fgf2 elisa kit
Rat Heparin-binding growth factor 2 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
activates the MAP kinase signaling pathway; plays a role in synaptic transmission; induces cell proliferation [RGD, Feb 2006]
Uniprot Description
FGF2: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Interacts with CSPG4, FGFBP1 and TEC. Found in a complex with FGFBP1, FGF1 and FGF2. Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue. Belongs to the heparin-binding growth factors family. 4 isoforms of the human protein are produced by alternative initiation.
Protein type: Activator; Motility/polarity/chemotaxis
Cellular Component: cytoplasm; extracellular space; nucleus
Molecular Function: chemoattractant activity; cytokine activity; fibroblast growth factor receptor binding; growth factor activity; heparin binding; ligand-dependent nuclear receptor transcription coactivator activity; protein binding
Biological Process: activation of MAPKK activity; adrenocorticotropin hormone secreting cell differentiation; aging; angiogenesis; cell migration during sprouting angiogenesis; embryonic development ending in birth or egg hatching; fibroblast growth factor receptor signaling pathway; glial cell differentiation; growth factor dependent regulation of satellite cell proliferation; hyaluronan catabolic process; induction of an organ; inositol phosphate biosynthetic process; lung development; negative regulation of blood vessel endothelial cell migration; negative regulation of cell proliferation; phosphatidylinositol biosynthetic process; positive chemotaxis; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; positive regulation of cardiac muscle cell proliferation; positive regulation of cell differentiation; positive regulation of cell division; positive regulation of cell fate specification; positive regulation of cell proliferation; positive regulation of endothelial cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of granule cell precursor proliferation; positive regulation of MAP kinase activity; positive regulation of osteoblast differentiation; positive regulation of phosphoinositide 3-kinase activity; positive regulation of protein amino acid phosphorylation; positive regulation of protein kinase B signaling cascade; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of cell cycle; regulation of retinal cell programmed cell death; release of sequestered calcium ion into cytosol; response to axon injury; stem cell development; substantia nigra development; thyroid stimulating hormone secreting cell differentiation; ureteric bud branching; wound healing
Research Articles on Fgf2
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Product Notes
The Rat Fgf2 fgf2 (Catalog #AAA2887131) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2887131 ELISA Kit recognizes Rat Fgf2. It is sometimes possible for the material contained within the vial of "Heparin-binding growth factor 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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