Western Blot (WB)
(Western blot analysis of extracts of Rat lung using ZGPAT Polyclonal Antibody at dilution of 1:1000.)
Rabbit anti-Rat ZGPAT Polyclonal Antibody | anti-ZGPAT antibody
ZGPAT Polyclonal Antibody
Gene Names
ZGPAT; ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847
Reactivity
Rat
Applications
Western Blot
Purity
Affinity purification
Synonyms
ZGPAT; Polyclonal Antibody; ZGPAT Polyclonal Antibody; GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZIP; anti-ZGPAT antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-ZGPAT antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human ZGPAT (NP_8521502)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of extracts of Rat lung using ZGPAT Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western blot analysis of extracts of Rat lung using ZGPAT Polyclonal Antibody at dilution of 1:1000.)
Related Product Information for anti-ZGPAT antibody
ZGPAT (Zinc finger CCCH-type with G patch domain-containing protein), also known as zinc finger CCCH domain-containing protein 9 (ZC3HDC9) and G patch domain-containing protein 6 (GPATC6), is a 531 amino acid protein that contains a G-patch domain, which is typically found within RNA-binding proteins. Proteins that contain the G-patch domain include some tumor suppressor and DNA-damage repair proteins. ZGPAT also contains one C3H1-type zinc finger, which further supports its probable role as an RNA-binding protein. The gene encoding ZGPAT is inactivated via differential methylation in a oligodendroglioma cell line, suggesting that ZGPAT may have utility as a biomarker. There are two isoforms of ZGPAT that are produced as a result of alternative splicing events.
Product Categories/Family for anti-ZGPAT antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,697 Da
NCBI Official Full Name
zinc finger CCCH-type with G patch domain-containing protein isoform a
NCBI Official Synonym Full Names
zinc finger, CCCH-type with G patch domain
NCBI Official Symbol
ZGPAT
NCBI Official Synonym Symbols
ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847
NCBI Protein Information
zinc finger CCCH-type with G patch domain-containing protein; g patch domain-containing protein 6; zinc finger CCCH domain-containing protein 9; zinc finger and G patch domain-containing protein
UniProt Protein Name
Zinc finger CCCH-type with G patch domain-containing protein
UniProt Gene Name
ZGPAT
UniProt Synonym Gene Names
GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZIP
UniProt Entry Name
ZGPAT_HUMAN
Uniprot Description
ZGPAT: Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 20q13.3
Cellular Component: nucleus
Molecular Function: protein binding; sequence-specific DNA binding; metal ion binding; transcription factor activity
Biological Process: negative regulation of epidermal growth factor receptor activity; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent
Research Articles on ZGPAT
Similar Products
Product Notes
The ZGPAT zgpat (Catalog #AAA2565696) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZGPAT Polyclonal Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZGPAT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the ZGPAT zgpat for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZGPAT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
