Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 47485(ZGPAT / Antibody) at dilution 1/60.(Original magnification: 200))
Rabbit anti-Human ZGPAT Polyclonal Antibody | anti-ZGPAT antibody
ZGPAT Antibody
Gene Names
ZGPAT; ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
ZGPAT ; Polyclonal Antibody; ZGPAT Antibody; ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847; RP4-583P15.3; anti-ZGPAT antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total ZGPAT / protein.
Purity/Purification
Antigen affinity purification
Form/Format
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.1 mg/mL (varies by lot)
Sequence Length
511
Applicable Applications for anti-ZGPAT antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-200
Immunogen
Synthetic peptide of human ZGPAT
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 47485(ZGPAT / Antibody) at dilution 1/60.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 47485(ZGPAT / Antibody) at dilution 1/60.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 47485(ZGPAT / Antibody) at dilution 1/60.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 47485(ZGPAT / Antibody) at dilution 1/60.(Original magnification: 200))
Related Product Information for anti-ZGPAT antibody
ZGPAT (Zinc finger CCCH-type with G patch domain-containing protein), also known as zinc finger CCCH domain-containing protein 9 (ZC3HDC9) and G patch domain-containing protein 6 (GPATC6), is a 531 amino acid protein that contains a G-patch domain, which is typically found within RNA-binding proteins. Proteins that contain the G-patch domain include some tumor suppressor and DNA-damage repair proteins. ZGPAT also contains one C3H1-type zinc finger, which further supports its probable role as an RNA-binding protein. The gene encoding ZGPAT is inactivated via differential methylation in a oligodendroglioma cell line, suggesting that ZGPAT may have utility as a biomarker. There are two isoforms of ZGPAT that are produced as a result of alternative splicing events.
Product Categories/Family for anti-ZGPAT antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,500 Da
NCBI Official Full Name
zinc finger CCCH-type with G patch domain-containing protein isoform c
NCBI Official Synonym Full Names
zinc finger CCCH-type and G-patch domain containing
NCBI Official Symbol
ZGPAT
NCBI Official Synonym Symbols
ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847
NCBI Protein Information
zinc finger CCCH-type with G patch domain-containing protein
UniProt Protein Name
Zinc finger CCCH-type with G patch domain-containing protein
UniProt Gene Name
ZGPAT
UniProt Synonym Gene Names
GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZIP
Uniprot Description
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.
Research Articles on ZGPAT
Similar Products
Product Notes
The ZGPAT zgpat (Catalog #AAA9430467) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZGPAT Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZGPAT can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-200. Researchers should empirically determine the suitability of the ZGPAT zgpat for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZGPAT , Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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