Western Blot (WB)
(L02 cells were subjected to SDS PAGE followed by western blot with MBS7605867 (ZGPAT antibody) at dilution of 1:1000)
Rabbit anti-Human, Mouse ZGPAT Polyclonal Antibody | anti-ZGPAT antibody
ZGPAT Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Western Blot (WB)
(L02 cells were subjected to SDS PAGE followed by western blot with MBS7605867 (ZGPAT antibody) at dilution of 1:1000)
Western Blot (WB)
(L02 cells were subjected to SDS PAGE followed by western blot with MBS7605867 (ZGPAT antibody) at dilution of 1:1000)
NCBI and Uniprot Product Information
Uniprot Description
ZGPAT: Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 20q13.3
Cellular Component: nucleus
Molecular Function: metal ion binding; protein binding; sequence-specific DNA binding; transcription factor activity
Biological Process: negative regulation of epidermal growth factor receptor activity; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on ZGPAT
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Product Notes
The ZGPAT zgpat (Catalog #AAA7605867) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZGPAT Rabbit Polyclonal reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZGPAT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the ZGPAT zgpat for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZGPAT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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