Limbic System-Associated Membrane Recombinant Protein | LSAMP recombinant protein

Recombinant Human Limbic System-Associated Membrane Protein

Cat. Num. AAA2556645

• Gene Names: LSAMP; LAMP; IGLON3
• Purity: >90% as determined by reducing SDS-PAGE.
• Synonyms: Limbic System-Associated Membrane; Recombinant Human Limbic System-Associated Membrane Protein; Limbic system-associated membrane protein; LSAMP; IgLON family member 3; LSAMP recombinant protein

• Host: Human Cells
• Purity/Purification: >90% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
• Sequence Length: 361

• Species: Human
• Endotoxin: <1.0 EU per ug as determined by LAL test.
• Fragment: Val29-Asn315
• Fusion Tag: C-6His
• Preparation and Storage: Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.; Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.; Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.

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Related Product Information for LSAMP recombinant protein

Protein Construction: Recombinant Human Limbic system-associated membrane protein is produced by our Mammalian expression system and the target gene encoding Val29-Asn315 is expressed with a 6His tag at the C-terminus.

Background: Limbic system-associated membrane protein is also known as LSAMP, IgLON family member 3. In humans, it is encoded by the LSAMP gene. It belongs to the immunoglobulin superfamily and contains 3 Ig-like C2-type domains. Limbic system-associated membrane protein mediates selective neuronal growth and axon targeting. It contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. It is also essential for normal growth of the hyppocampal mossy fiber projection

NCBI and Uniprot Product Information

• NCBI GI #: 974576775
• NCBI GeneID: 4045
• NCBI Accession #: NP_001305844.1
• NCBI GenBank Nucleotide #: NM_001318915.1
• UniProt Accession #: Q13449; Q8IV49
• Molecular Weight: Molecular Mass: 32.8kDa; Actual Protein Molecular Mass: 55kDa
• NCBI Official Full Name: limbic system-associated membrane protein isoform 2
• NCBI Official Synonym Full Names: limbic system associated membrane protein
• NCBI Official Symbol: LSAMP
• NCBI Official Synonym Symbols: LAMP; IGLON3
• NCBI Protein Information: limbic system-associated membrane protein
• UniProt Protein Name: Limbic system-associated membrane protein
• Protein Family: Limbic system-associated membrane protein
• UniProt Gene Name: LSAMP
• UniProt Synonym Gene Names: IGLON3; LAMP; LSAMP

NCBI Description

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Uniprot Description

Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection ().