T-lymphocyte Activation Antigen CD80/B7-1 Recombinant Protein | Cd80 recombinant protein
Recombinant Rat T-lymphocyte Activation Antigen CD80/B7-1 Protein (C-6His)
Gene Names
Cd80; B7-1
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
T-lymphocyte Activation Antigen CD80/B7-1; Recombinant Rat T-lymphocyte Activation Antigen CD80/B7-1 Protein (C-6His); T-lymphocyte activation antigen CD80; Activation B7-1 antigen; B7; CD80; Cd80 recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of PBS, pH 7.4.
Sequence Positions
Vla30-Gln248
Sequence Length
321
Species
Rat
Endotoxin
<1.0 EU per mug as determined by LAL test.
Fusion Tag
C-6His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for Cd80 recombinant protein
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 25.7 kDa
Actual Protein Molecular Mass: 38 kDa
Actual Protein Molecular Mass: 38 kDa
NCBI Official Full Name
T-lymphocyte activation antigen CD80
NCBI Official Synonym Full Names
Cd80 molecule
NCBI Official Symbol
Cd80
NCBI Official Synonym Symbols
B7-1
NCBI Protein Information
T-lymphocyte activation antigen CD80
UniProt Protein Name
B7.1
Protein Family
UniProt Gene Name
Cd80
UniProt Synonym Gene Names
B7.1ImportedAutomatic assertion inferred from database entriesiEMBL:AAB66351.1
NCBI Description
cell surface protein that is part of the immune response; may be involved in induction of experimental autoimmune anterior uveitis [RGD, Feb 2006]
Research Articles on Cd80
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Product Notes
The Cd80 cd80 (Catalog #AAA2553674) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Vla30-Gln248. It is sometimes possible for the material contained within the vial of "T-lymphocyte Activation Antigen CD80/B7-1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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