Apolipoprotein E/ApoE Recombinant Protein | ApoE recombinant protein

Recombinant Mouse Apolipo Protein E/ApoE Protein (C-6His)

Cat. Num. AAA2553444

• Gene Names: Apoe; Apo-E; AI255918
• Purity: >95% as determined by reducing SDS-PAGE.
• Synonyms: Apolipoprotein E/ApoE; Recombinant Mouse Apolipo Protein E/ApoE Protein (C-6His); Apolipoprotein E; Apo-E; APOE; ApoE recombinant protein

• Host: Human Cells
• Purity/Purification: >95% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
• Sequence Positions: Glu19-Gln311
• Sequence Length: 311

• Species: Mouse
• Endotoxin: <1.0 EU per mug as determined by LAL test.
• Fusion Tag: C-6His
• Preparation and Storage: Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.; Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.

Related Product Information for ApoE recombinant protein

Apolipoprotein E (Apo-E), is a member of the apolipoprotein A1/A4/E family. ApoE is a major protein component of serum LDL, VLDL, HDL, and chylomicrons. APOE may function in mediating the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. APOE is usually secreted in plasma. Phosphorylation sites are present in the extracellular medium.

NCBI and Uniprot Product Information

• NCBI GI #: 802084029
• NCBI GeneID: 11816
• NCBI Accession #: NP_001292748.1
• NCBI GenBank Nucleotide #: NM_001305819.1
• UniProt Accession #: P08226
• Molecular Weight: Molecular Mass: 35.0 kDa; Actual Protein Molecular Mass: 37 kDa
• NCBI Official Full Name: apolipoprotein E
• NCBI Official Synonym Full Names: apolipoprotein E
• NCBI Official Symbol: Apoe
• NCBI Official Synonym Symbols: Apo-E; AI255918
• NCBI Protein Information: apolipoprotein E
• UniProt Protein Name: Apolipoprotein E
• Protein Family: Apolipoprotein
• UniProt Gene Name: Apoe
• UniProt Synonym Gene Names: Apo-E

NCBI Description

This gene encodes a member of the apolipoprotein A1/A4/E family of proteins. This protein is involved in the transport of lipoproteins in the blood. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Homozygous knockout mice for this gene accumulate high levels of cholesterol in the blood and develop atherosclerosis. Different alleles of this gene have been associated with either increased risk or a protective effect for Alzheimer's disease in human patients. This gene maps to chromosome 7 in a cluster with the related apolipoprotein C1, C2 and C4 genes. [provided by RefSeq, Apr 2015]

Uniprot Description

Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.