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Western Blot (WB) (Western Blot analysis of 293T cells using IKKalpha Polyclonal Antibody at dilution of 1:1000.)

IKK Isoform Antibody Kit | IKK antibody kit

IKK Isoform Antibody Sampler Kit

Applications
Western Blot
Synonyms
IKK Isoform; IKK Isoform Antibody Sampler Kit; IKK antibody kit
Ordering
For Research Use Only!
Applicable Applications for IKK antibody kit
Western Blot (WB)

Western Blot (WB)

(Western Blot analysis of 293T cells using IKKalpha Polyclonal Antibody at dilution of 1:1000.)

Western Blot (WB) (Western Blot analysis of 293T cells using IKKalpha Polyclonal Antibody at dilution of 1:1000.)

Western Blot (WB)

(Western Blot analysis of 293 cells with IKKbeta Polyclonal Antibody.)

Western Blot (WB) (Western Blot analysis of 293 cells with IKKbeta Polyclonal Antibody.)

Western Blot (WB)

(Western Blot analysis of COS7 cells with IKKgamma Polyclonal Antibody.)

Western Blot (WB) (Western Blot analysis of COS7 cells with IKKgamma Polyclonal Antibody.)

Western Blot (WB)

(Western Blot analysis of Raji cell using IKBKE Polyclonal Antibody at dilution of 1:400)

Western Blot (WB) (Western Blot analysis of Raji cell using IKBKE Polyclonal Antibody at dilution of 1:400)
Related Product Information for IKK antibody kit
Background: The NF-kappaB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IkappaB proteins. Most agents that activate NF-kappaB do so through a common pathway based on phosphorylation-induced, proteasome-mediated degradation of IkappaB. The key regulatory step in this pathway involves activation of a high molecular weight IkappaB kinase (IKK) complex whose catalysis is generally carried out by three tightly associated IKK subunits. IKKalpha and IKKbeta serve as the catalytic subunits of the kinase and IKKgamma serves as the regulatory subunit. Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKKbeta (Ser176 and Ser180 in IKKalpha), which causes conformational changes, resulting in kinase activation.

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Product Notes

The IKK (Catalog #AAA2550054) is an Antibody Kit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IKK Isoform can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the IKK for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IKK Isoform, Antibody Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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