SDS-PAGE
C4.4A / LYPD3 recombinant protein
Recombinant Human C4.4A / LYPD3 Protein (His tag)
Gene Names
LYPD3; C4.4A
Purity
> 95 % as determined by SDS-PAGE
Synonyms
C4.4A / LYPD3; Recombinant Human C4.4A / LYPD3 Protein (His tag); UNQ491/PRO1007; C4.4A; C4.4A / LYPD3 recombinant protein
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
346
Application Notes
The recombinant human LYPD3 consists of 267 amino acids and predictes a molecular mass of 28.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhLYPD3 is approximately 45-60 kDa due to glycosylation.
Predicted N Terminal
Leu 31
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for C4.4A / LYPD3 recombinant protein
Background: Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4 and LYPD3, is a cell membrane protein which contains two UPAR/Ly6 domains. Human LYPD3 contains two UPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression
Description: A DNA sequence encoding the human LYPD3 (NP_055215.2) C-terminal segment (Met 1-His 286) was expressed, with a polyhistidine tag at the C-terminus.
Description: A DNA sequence encoding the human LYPD3 (NP_055215.2) C-terminal segment (Met 1-His 286) was expressed, with a polyhistidine tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,971 Da
NCBI Official Full Name
ly6/PLAUR domain-containing protein 3
NCBI Official Synonym Full Names
LY6/PLAUR domain containing 3
NCBI Official Symbol
LYPD3
NCBI Official Synonym Symbols
C4.4A
NCBI Protein Information
ly6/PLAUR domain-containing protein 3
UniProt Protein Name
Ly6/PLAUR domain-containing protein 3
UniProt Gene Name
LYPD3
UniProt Synonym Gene Names
C4.4A; MIG-C4
Uniprot Description
LYPD3: Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.
Protein type: Cell adhesion; Membrane protein, GPI anchor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 19q13.31
Cellular Component: anchored to plasma membrane; extracellular space
Molecular Function: laminin binding
Biological Process: cell-matrix adhesion
Research Articles on C4.4A / LYPD3
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Product Notes
The C4.4A / LYPD3 lypd3 (Catalog #AAA2545653) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant human LYPD3 consists of 267 amino acids and predictes a molecular mass of 28.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhLYPD3 is approximately 45-60 kDa due to glycosylation. Researchers should empirically determine the suitability of the C4.4A / LYPD3 lypd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C4.4A / LYPD3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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