Testing Data
(P-peptide-+)
SLP-76 Antibody | anti-SLP-76 antibody
SLP-76 (Phospho-Tyr128) Antibody
Gene Names
LCP2; SLP76; SLP-76
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Synonyms
SLP-76; SLP-76 (Phospho-Tyr128) Antibody; LCP2; Lymphocyte cytosolic protein 2; SH2 domain-containing leucocyte protein of 76 kDa; SLP-76 tyrosine phosphoprotein; anti-SLP-76 antibody
Reactivity
Human, Mouse, Rat
Specificity
SLP-76 (Phospho-Tyr128) antibody detects endogenous levels of SLP-76 only when phosphorylated at tyrosine 128.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
533
Applicable Applications for anti-SLP-76 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:1000
IHC: 1:50~1:100
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human SLP-76 around the phosphorylation site of tyrosine 128 (G-D-YP-E-S).
All Sites
Human: Tyr128
Mouse: Tyr128
Rat: Tyr128
Mouse: Tyr128
Rat: Tyr128
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
(P-peptide-+)
Testing Data
(P-peptide-+)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using SLP-76 (Phospho-Tyr128) antibody. Western blot analysis of extracts from K562 cells, treated with Na3VO4 (0.3nM, 40mins), using SLP-76 (Phospho-Tyr128) antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using SLP-76 (Phospho-Tyr128) antibody. Western blot analysis of extracts from K562 cells, treated with Na3VO4 (0.3nM, 40mins), using SLP-76 (Phospho-Tyr128) antibody.)
References
Jackman J.K., J. Biol. Chem. 270:7029-7032(1995). The MGC Project Team; Genome Res. 14:2121-2127(2004). Moog-Lutz C., J. Biol. Chem. 276:22375-22381(2001).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
60,188 Da
NCBI Official Full Name
lymphocyte cytosolic protein 2
NCBI Official Synonym Full Names
lymphocyte cytosolic protein 2
NCBI Official Symbol
LCP2
NCBI Official Synonym Symbols
SLP76; SLP-76
NCBI Protein Information
lymphocyte cytosolic protein 2
UniProt Protein Name
Lymphocyte cytosolic protein 2
UniProt Gene Name
LCP2
UniProt Synonym Gene Names
SLP76
NCBI Description
This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability. [provided by RefSeq, Nov 2016]
Uniprot Description
Involved in T-cell antigen receptor mediated signaling.
Research Articles on SLP-76
Similar Products
Product Notes
The SLP-76 lcp2 (Catalog #AAA8510335) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The SLP-76 (Phospho-Tyr128) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLP-76 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000. Researchers should empirically determine the suitability of the SLP-76 lcp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLP-76, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
