Rabbit anti-Mouse SLC3A2  Monoclonal Antibody | anti-SLC3A2  antibody

Rabbit anti Mouse SLC3A2  Monoclonal Antibody

Cat. Num. AAA2544664

• Gene Names: slc3a2a; slc3a2; fc65h12; wu:fc65h12
• Reactivity: Mouse
• Applications: ELISA
• Synonyms: SLC3A2 ; Monoclonal Antibody; Rabbit anti Mouse SLC3A2 Monoclonal Antibody; anti-SLC3A2 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Monoclonal
• Isotype: IgG
• Sequence Length: 485

• Applicable Applications for anti-SLC3A2 antibody: ELISA (EIA)
• Application Notes: ELISA: 0.1-0.2 mug/mL. This antibody can be used at 0.1-0.2 mug/mL with the appropriate secondary reagents to detect Mouse SLC3A2. The detection limit for Mouse SLC3A2 is approximately 0.00245 ng/well.
• Immunogen: Recombinant Mouse SLC3A2 protein
• Buffer: 0.2 mum filtered solution in PBS with 5% trehalose
• Preparation and Storage: This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Related Product Information for anti-SLC3A2  antibody

4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein which belongs to the SLC3A transporter family. SLC3A2/MDU1 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. During gestation, expression in the placenta is significantly stronger at full-term than at the mid-trimester stage. SLC3A2/MDU1 is expressed in HUVECS and at low levels in resting peripheral blood T-lymphocytes and quiescent fibroblasts. It is expressed in fetal liver and in the astrocytic process of primary astrocytic gliomas. SLC3A2/MDU1 is also expressed in retinal endothelial cells and in the intestinal epithelial cell line Caco2-BBE. SLC3A2/MDU1 is required for the function of light chain amino-acid transporters. It involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. SLC3A2/MDU1 is involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7, SLC3A2/MDU1 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. SLC3A2/MDU1 plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. It is required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, SLC3A2/MDU1 is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta.

NCBI and Uniprot Product Information

• NCBI GI #: 849602903
• NCBI GeneID: 796322
• NCBI GenBank Nucleotide #: NM_131601.2
• NCBI Official Full Name: solute carrier family 3 (amino acid transporter heavy chain), member 2a
• NCBI Official Synonym Full Names: solute carrier family 3 (amino acid transporter heavy chain), member 2a
• NCBI Official Symbol: slc3a2a
• NCBI Official Synonym Symbols: slc3a2; fc65h12; wu:fc65h12
• NCBI Protein Information: solute carrier family 3 (amino acid transporter heavy chain), member 2a