Rabbit anti-Human PRSS3 Monoclonal Antibody | anti-PRSS3 antibody
Rabbit anti Human PRSS3 Monoclonal Antibody
Gene Names
PRSS3; T9; MTG; TRY3; TRY4; PRSS4
Reactivity
Human
Applications
ELISA
Synonyms
PRSS3 ; Monoclonal Antibody; Rabbit anti Human PRSS3 Monoclonal Antibody; anti-PRSS3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Sequence Length
247
Applicable Applications for anti-PRSS3 antibody
ELISA (EIA)
Application Notes
ELISA: 0.1-0.2 mug/mL. This antibody can be used at 0.1-0.2 mug/mL with the appropriate secondary reagents to detect Human PRSS3. The detection limit for Human PRSS3 is approximately 0.00245 ng/well.
Immunogen
Recombinant Human Trypsin-3/PRSS3 protein
Buffer
0.2 mum filtered solution in PBS with 5% trehalose
Preparation and Storage
This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-PRSS3 antibody
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein which belongs to the peptidase S1 family. Trypsin-3/PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3/PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their inhibitors seems to be important for the development of CP. The trypsin inhibitor-degrading activity qualified PRSS3 as a candidate for a novel CP susceptibility gene. Trypsin-3/PRSS3 has been implicated as a putative tumor suppressor gene due to its loss of expression, which is correlated with promoter hypermethylation, in esophageal squamous cell carcinoma and gastric adenocarcinoma.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
25,924 Da
NCBI Official Full Name
PRSS3 protein
NCBI Official Synonym Full Names
protease, serine 3
NCBI Official Symbol
PRSS3
NCBI Official Synonym Symbols
T9; MTG; TRY3; TRY4; PRSS4
NCBI Protein Information
trypsin-3
UniProt Protein Name
Trypsin-3
UniProt Gene Name
PRSS3
UniProt Synonym Gene Names
PRSS4; TRY3; TRY4
UniProt Entry Name
TRY3_HUMAN
NCBI Description
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010]
Uniprot Description
Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5.
Research Articles on PRSS3
Similar Products
Product Notes
The PRSS3 prss3 (Catalog #AAA2544304) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human PRSS3 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PRSS3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 0.1-0.2 mug/mL. This antibody can be used at 0.1-0.2 mug/mL with the appropriate secondary reagents to detect Human PRSS3. The detection limit for Human PRSS3 is approximately 0.00245 ng/well. Researchers should empirically determine the suitability of the PRSS3 prss3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRSS3 , Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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