Rabbit anti-Human SPARCL1 Monoclonal Antibody | anti-SPARCL1 antibody
Rabbit anti Human SPARCL1 Monoclonal Antibody
Gene Names
SPARCL1; SC1; MAST9; PIG33; MAST 9
Reactivity
Human
Applications
ELISA
Synonyms
SPARCL1 ; Monoclonal Antibody; Rabbit anti Human SPARCL1 Monoclonal Antibody; anti-SPARCL1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Sequence Length
539
Applicable Applications for anti-SPARCL1 antibody
ELISA (EIA)
Application Notes
ELISA: 0.1-0.2 mug/mL. This antibody can be used at 0.1-0.2 mug/mL with the appropriate secondary reagents to detect Human SPARCL1. The detection limit for Human SPARCL1 is approximately 0.039 ng/well.
Immunogen
Recombinant Human SPARCL1 protein
Buffer
This antibody was obtained from a rabbit immunized with purified, recombinant Human SPARCL1 (rhSPARCL1; NP_004675.3; Met 1-Phe 664).
Preparation and Storage
This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -70 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-SPARCL1 antibody
SPARC-like protein 1 (SPARCL1; also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins. It contains three conserved structural domains that are implicated in the regulation of cell adhesion, migration, and proliferation. SPARCL1 is expressed during embryogenesis and tissue remodeling and is especially prominent in brain and vasculature. Its down-regulation in a number of cancers and the possibility of its functional compensation by SPARC has led to recent interest in hevin as a tumor suppressor and regulator of angiogenesis. SPARCL1 has antiadhesive properties, and loss of SPARCL1 expression is associated with increased proliferative activity and cell cycle progression. It is suggested that it may influence multiple cellular processes during distinct stages of brain development and function. In addition, SPARCL1 can influence the function of astroglial cells in the developing and mature central nervous system (CNS).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
61,760 Da
NCBI Official Full Name
SPARC-like protein 1 isoform 2
NCBI Official Synonym Full Names
SPARC like 1
NCBI Official Symbol
SPARCL1
NCBI Official Synonym Symbols
SC1; MAST9; PIG33; MAST 9
NCBI Protein Information
SPARC-like protein 1
UniProt Protein Name
SPARC-like protein 1
UniProt Gene Name
SPARCL1
UniProt Synonym Gene Names
Hevin
UniProt Entry Name
SPRL1_HUMAN
Uniprot Description
SPARCL1: Belongs to the SPARC family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q22.1
Cellular Component: extracellular space
Molecular Function: calcium ion binding; collagen binding; extracellular matrix binding
Biological Process: anatomical structure development
Research Articles on SPARCL1
Similar Products
Product Notes
The SPARCL1 sparcl1 (Catalog #AAA2543816) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human SPARCL1 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPARCL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 0.1-0.2 mug/mL. This antibody can be used at 0.1-0.2 mug/mL with the appropriate secondary reagents to detect Human SPARCL1. The detection limit for Human SPARCL1 is approximately 0.039 ng/well. Researchers should empirically determine the suitability of the SPARCL1 sparcl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPARCL1 , Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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