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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using LEO1 Polyclonal Antibody at dilution 1:20)

Rabbit LEO1 Polyclonal Antibody | anti-LEO1 antibody

LEO1 Polyclonal Antibody

Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
LEO1; Polyclonal Antibody; LEO1 Polyclonal Antibody; RDL; anti-LEO1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.4mg/mL (varies by lot)
Sequence Length
464
Applicable Applications for anti-LEO1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:25-1:100
Immunogen
Synthetic peptide of human LEO1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using LEO1 Polyclonal Antibody at dilution 1:20)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using LEO1 Polyclonal Antibody at dilution 1:20)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using LEO1 Polyclonal Antibody at dilution 1:20)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using LEO1 Polyclonal Antibody at dilution 1:20)
Related Product Information for anti-LEO1 antibody
LEO1, parafibromin (CDC73; MIM 607393), CTR9 (MIM 609366), and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex 

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
53,920 Da
NCBI Official Full Name
LEO1
UniProt Protein Name
RNA polymerase-associated protein LEO1
UniProt Gene Name
LEO1
UniProt Entry Name
LEO1_YEAST

Uniprot Description

The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. It regulates 3'-end formation of snR47 by modulating the recruitment or stable association of NRD1 and NAB3 with RNA polymerase II. Also has a role in transcription-coupled histone modification. Required for activation of RAD6 ubiquitin conjugate and the BRE1 ubiquitin ligase which ubiquitinate 'Lys-126' histone H2B. Activates the SET1 histone methyltransferase complex for methylation of 'Lys-4' of histone H3 and for methylation of 'Lys-73' of histone H3 by DOT1 and 'Lys-36' of histone H3 by SET2.

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Product Notes

The LEO1 leo1 (Catalog #AAA2520366) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LEO1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LEO1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:25-1:100. Researchers should empirically determine the suitability of the LEO1 leo1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LEO1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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