Structure
AZD 2098 Biochemical
AZD 2098
Purity
>98% (HPLC)
Synonyms
AZD 2098; AZD2098; AZD-2098; AZD 2098 biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: Soluble (<1mg/mL refers to the product slightly soluble or insoluble)
Target
Chemokine Receptor
Receptor
CCR4
Chemical Name
2, 3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide
SMILES
O=S(C1=CC=CC(Cl)=C1Cl)(NC2=NC=CN=C2OC)=O
Molecular Formula
C11H9Cl2N3O3S
CAS Number
566203-88-1
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for AZD 2098 biochemical
AZD2098 is a potent, selective, orally bioavailable CCR4 receptor antagonist with pIC50 of 7.8 for hCCR4, pIC50 of 8.0 for rCCR4; shows no significant activity against a panel of chemokine receptors (CXCR1, CXCR2, CCR1, CCR2b, CCR5, CCR7, CCR8; inactive at 10uM); inhibits Th2 cell CCL22 driven chemotaxis in 0.3% HSA with pIC50 of 6.3; exhibits anti-inflammatory effects in Brown-Norway rats sensitized to ovalbumin. Asthma Phase 1 Clinical
Product Categories/Family for AZD 2098 biochemical
References
1. Kindon N, et al. ACS Med Chem Lett. 2017 Sep 1; 8 (9):981-986.
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Product Notes
The AZD 2098 (Catalog #AAA3605056) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "AZD 2098, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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