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Immunohistochemistry (IHC) (Anti-SCARA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Rabbit anti-Human, Mouse SCARA5 Polyclonal Antibody | anti-SCARA5 antibody

Rabbit Polyclonal to Human SCARA5

Gene Names
SCARA5; Tesr; NET33
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Immunocytochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
SCARA5; Polyclonal Antibody; Rabbit Polyclonal to Human SCARA5; Anti-SCARA5 Antibody (C-Terminus) IHC-plus; Tesr; NET33; Scavenger receptor hlg; Human SCARA5; anti-SCARA5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Human SCARA5
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.02% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
495
Applicable Applications for anti-SCARA5 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, ICC, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: SCARA5 antibody can be used for detection of SCARA5 by Western blot at 1-2 ug/ml. Antibody does not work to detect mouse SCARA5 in Western blot.
Target Species
Human
Immunogen Description
A 17 amino acid peptide near the carboxy terminus of human SCARA5.
Immunogen Type
Synthetic peptide
Immunogen
SCARA5 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SCARA5.
Antigen Modification
C-Terminus
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-SCARA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-SCARA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of SCARA5 in HepG2 cells with SCARA5 antibody at 20 ug/ml.)

Immunofluorescence (IF) (Immunofluorescence of SCARA5 in HepG2 cells with SCARA5 antibody at 20 ug/ml.)

Immunocytochemistry (ICC)

(Immunocytochemistry of SCARA5 in HepG2 cells with SCARA5 antibody at 2.5 ug/ml.)

Immunocytochemistry (ICC) (Immunocytochemistry of SCARA5 in HepG2 cells with SCARA5 antibody at 2.5 ug/ml.)

Western Blot (WB)

(Western blot of SCARA5 in human liver tissue lysate with SCARA5 antibody at 1 ug/ml.)

Western Blot (WB) (Western blot of SCARA5 in human liver tissue lysate with SCARA5 antibody at 1 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,871 Da
NCBI Official Full Name
scavenger receptor class A member 5
NCBI Official Synonym Full Names
scavenger receptor class A, member 5
NCBI Official Symbol
SCARA5
NCBI Official Synonym Symbols
Tesr; NET33
NCBI Protein Information
scavenger receptor class A member 5; scavenger receptor hlg; testis expressed scavenger receptor; scavenger receptor class A, member 5 (putative)
UniProt Protein Name
Scavenger receptor class A member 5
Protein Family
UniProt Gene Name
SCARA5
UniProt Entry Name
SCAR5_HUMAN

Uniprot Description

SCARA5: Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). Belongs to the SCARA5 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p21.1

Cellular Component: cell surface; integral to plasma membrane

Molecular Function: scavenger receptor activity

Biological Process: receptor-mediated endocytosis; regulation of gene expression; cellular iron ion homeostasis; regulation of blood coagulation; endocytosis

Research Articles on SCARA5

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Product Notes

The SCARA5 scara5 (Catalog #AAA247854) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human SCARA5 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SCARA5 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), ELISA (EIA). ELISA, ICC, IHC-P (5 ug/ml), WB (1 - 2 ug/ml) Usage: SCARA5 antibody can be used for detection of SCARA5 by Western blot at 1-2 ug/ml. Antibody does not work to detect mouse SCARA5 in Western blot. Researchers should empirically determine the suitability of the SCARA5 scara5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SCARA5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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