Immunohistochemistry (IHC)
(Anti-MAPK15 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Rabbit anti-Human MAPK15 / ERK7 Polyclonal Antibody | anti-MAPK15 antibody
Rabbit Polyclonal (IgG) to Human MAPK15 / ERK7
Gene Names
MAPK15; ERK7; ERK8
Reactivity
Human
Applications
Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Western Blot
Purity
Immunoaffinity Purified
Synonyms
MAPK15 / ERK7; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human MAPK15 / ERK7; Anti-MAPK15 / ERK7 Antibody IHC-plus; MAPK15; ERK7; ERK-8; MAPK 15; MAP kinase 15; ERK-7; ERK8; Human MAPK15; anti-MAPK15 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human MAPK15.
Purity/Purification
Immunoaffinity Purified
Form/Format
0.1 M Tris-glycine, pH 7, 10% Glycerol, 0.01% Thimerosal
Concentration
1 mg/ml (varies by lot)
Sequence Length
544
Applicable Applications for anti-MAPK15 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB)
Application Notes
ICC (1:100 - 1:200), IF (1:100 - 1:200), IHC-P (10 ug/ml), WB (1:500 - 1:3000)
Target Species
Human
Immunogen Description
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 245 (Q8TD08) of MAPK15.
Immunogen Type
Recombinant protein
Immunogen
MAPK15 / ERK7 antibody was raised against recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 245 (Q8TD08) of MAPK15.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Immunohistochemistry (IHC)
(Anti-MAPK15 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Immunohistochemistry (IHC)
(Anti-MAPK15 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Immunofluorescence (IF)
(Immunofluorescence of methanol-fixed A431, using MAPK15 antibody at 1:200 dilution.)
Immunofluorescence (IF)
(Immunofluorescence of methanol-fixed A431, using MAPK15 antibody at 1:200 dilution.)
Western Blot (WB)
(Sample. A: 30g of HeLa S3 whole cell lysate. 7.5% SDS PAGE. MAPK15 antibody diluted at 1:1000)
Western Blot (WB)
(Sample. A: 30g of HeLa S3 whole cell lysate. 7.5% SDS PAGE. MAPK15 antibody diluted at 1:1000)
Related Product Information for anti-MAPK15 antibody
ERK8 is a MAPK type protein kinase that is activated by a Src-dependent signaling pathway. The protein contains two SH3-binding motifs in its C-terminal region and has been shown to associate with the c-Src SH3 domain in vitro and co-immunoprecipitate with c-Src in vivo.
Product Categories/Family for anti-MAPK15 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,112 Da
NCBI Official Full Name
mitogen-activated protein kinase 15
NCBI Official Synonym Full Names
mitogen-activated protein kinase 15
NCBI Official Symbol
MAPK15
NCBI Official Synonym Symbols
ERK7; ERK8
NCBI Protein Information
mitogen-activated protein kinase 15; ERK-7; ERK-8; MAPK 15; MAP kinase 15; extracellular regulated kinase 8 delta; extracellular signal regulated kinase 8; extracellular signal-regulated kinase 7; extracellular signal-regulated kinase 8
UniProt Protein Name
Mitogen-activated protein kinase 15
UniProt Gene Name
MAPK15
UniProt Synonym Gene Names
ERK7; ERK8; MAP kinase 15; MAPK 15; ERK-7; ERK-8
UniProt Entry Name
MK15_HUMAN
Uniprot Description
ERK7: In vitro, phosphorylates MBP. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Kinase, protein; Protein kinase, CMGC; EC 2.7.11.24; Protein kinase, Ser/Thr (non-receptor); CMGC group; MAPK family; Erk7 subfamily
Chromosomal Location of Human Ortholog: -
Cellular Component: extracellular region; intracellular; nucleus
Molecular Function: MAP kinase activity; SH3 domain binding; ATP binding
Biological Process: positive regulation of protein ubiquitination; negative regulation of DNA replication; protein amino acid autophosphorylation; positive regulation of protein catabolic process; MAPKKK cascade; negative regulation of transcription from RNA polymerase II promoter; positive regulation of protein amino acid phosphorylation; response to estradiol stimulus
Research Articles on MAPK15
1. Data suggest that the model coulb be a tool for the development of specific ERK8 kinase inhibitors.
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Product Notes
The MAPK15 mapk15 (Catalog #AAA244075) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human MAPK15 / ERK7 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MAPK15 / ERK7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB). ICC (1:100 - 1:200), IF (1:100 - 1:200), IHC-P (10 ug/ml), WB (1:500 - 1:3000). Researchers should empirically determine the suitability of the MAPK15 mapk15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAPK15 / ERK7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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