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Rabbit anti-Rat Carcinoembryonic Antigen (CEA) Polyclonal Antibody | anti-CEA antibody

APC-Cy7 Linked Polyclonal Antibody to Carcinoembryonic Antigen (CEA)

Gene Names
Ceacam1; Bgp; BGPR; CD66a; Ccam1
Reactivity
Rat
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Synonyms
Carcinoembryonic Antigen (CEA); Polyclonal Antibody; APC-Cy7 Linked Polyclonal Antibody to Carcinoembryonic Antigen (CEA); CD66E; CD66; CEACAM5; Carcinoembryonic Antigen-related Cell Adhesion Molecule 5; Carcinoembryonic Antigen; anti-CEA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against CEA. It has been selected for its ability to recognize CEA in immunohistochemical staining and western blotting.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
>=100ug/ml (varies by lot)
Sequence
Asp209~Leu408
Applicable Applications for anti-CEA antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Immunogen Sequence
Asp209~Leu408
Cross Reactivity
Rat
Conjugation
APC-Cy7
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for anti-CEA antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,264 Da
NCBI Official Full Name
carcinoembryonic antigen-related cell adhesion molecule 1 isoform 1
NCBI Official Synonym Full Names
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
NCBI Official Symbol
Ceacam1
NCBI Official Synonym Symbols
Bgp; BGPR; CD66a; Ccam1
NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 1; GP110; pp120; C-CAM 105; ecto-ATPase; osteocalcin; cell-CAM 105; pp120/ecto-ATPase; ATP-dependent taurocolate-carrier protein; bone gamma-carboxyglutamic acid (Gla) protein; CEA-related cell adhes
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 1
Protein Family
UniProt Gene Name
Ceacam1
UniProt Synonym Gene Names
C-CAM 105
UniProt Entry Name
CEAM1_RAT

NCBI Description

glycoprotein component of bile; plays a role in cell adhesion [RGD, Feb 2006]

Uniprot Description

CEACAM1: carcinoembryonic antigen-related cell adhesion molecule 1. A cell-cell adhesion molecule that directly associates with annexin II. Has tumor suppressor activity in prostate carcinoma. Belongs to the immunoglobulin superfamily and the CEA family. Abundantly expressed in epithelia, vessel endothelia, trophoblasts, platelets and neutrophilic granulocytes. Also present in many cell types of the immune system such as B cells, T cells, NK cells, macrophages and dendritic cells. Five alternatively spliced isoforms have been described. Two isoforms are type I membrane proteins, while three are secreted.

Protein type: Membrane protein, integral; Immunoglobulin superfamily; Cell adhesion; Motility/polarity/chemotaxis

Cellular Component: extracellular space; membrane; integral to plasma membrane; brush border membrane; integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: viral receptor activity; protein homodimerization activity; virion binding; protein kinase binding

Biological Process: Peyer's patch development; negative regulation of JNK cascade; entry of virus into host cell; positive regulation of NFAT protein import into nucleus; positive regulation of JNK cascade; positive regulation of immunoglobulin secretion; signal transduction; calcium-independent cell-cell adhesion; negative regulation of interleukin-2 production; positive regulation of MAP kinase activity; negative regulation of T cell proliferation; negative regulation of cytokine production; calcium-dependent cell-cell adhesion; positive regulation of T cell proliferation; homophilic cell adhesion; cell adhesion

Research Articles on CEA

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Product Notes

The CEA ceacam1 (Catalog #AAA2116765) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APC-Cy7 Linked Polyclonal Antibody to Carcinoembryonic Antigen (CEA) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Carcinoembryonic Antigen (CEA) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CEA ceacam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Asp209~Leu 408. It is sometimes possible for the material contained within the vial of "Carcinoembryonic Antigen (CEA), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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