ANXA11 recombinant protein

ANXA11, 1-505aa, Human, His tag, E Coli

Cat. Num. AAA203822

• Gene Names: ANXA11; ALS23; ANX11; CAP50; CAP-50
• Applications: SDS-Page
• Purity: > 95% by SDS-PAGE
• Synonyms: ANXA11; 1-505aa; Human; His tag; E Coli; Annexin A11; ANX11; CAP50; Annexin-11; Annexin XI; ANXA11 recombinant protein

• Host: E Coli
• Purity/Purification: > 95% by SDS-PAGE
• Form/Format: Liquid. In PBS containing 20% glycerol, 2mM DTT, 100mM NaCl
• Concentration: 0.25mg/ml (determined by Bradford assay) (varies by lot)
• Sequence: MGSSHHHHHH SSGLVPRGSH MSYPGYPPPP GGYPPAAPGG GPWGGAAYPP PPSMPPIGLD NVATYAGQFN QDYLSGMAAN MSGTFGGANM PNLYPGAPGA GYPPVPPGGF GQPPSAQQPV PPYGMYPPPG GNPPSRMPSY PPYPGAPVPG QPMPPPGQQP PGAYPGQPPV TYPGQPPVPL PGQQQPVPSY PGYPGSGTVT PAVPPTQFGS RGTITDAPGF DPLRDAEVLR KAMKGFGTDE QAIIDCLGSR SNKQRQQILL SFKTAYGKDL IKDLKSELSG NFEKTILALM KTPVLFDIYE IKEAIKGVGT DEACLIEILA SRSNEHIREL NRAYKAEFKK TLEEAIRSDT SGHFQRLLIS LSQGNRDEST NVDMSLAQRD AQELYAAGEN RLGTDESKFN AVLCSRSRAH LVAVFNEYQR MTGRDIEKSI CREMSGDLEE GMLAVVKCLK NTPAFFAERL NKAMRGAGTK DRTLIRIMVS RSETDLLDIR SEYKRMYGKS LYHDISGDTS GDYRKILLKI CGGND
• Sequence Length: 505

• Applicable Applications for ANXA11 recombinant protein: SDS-PAGE
• Antigen Species: Human
• Tag Information: His-tag
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for ANXA11 recombinant protein

ANXA11 (Annexin A11) is a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. ANXA11 binds specifically to calcyclin in a calcium-dependent manner. And it required for midbody formation and completion of the terminal phase of cytokinesis. This protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Recombinant ANXA11 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.

Product Categories/Family for ANXA11 recombinant protein

Signal Transduction

References

Tomas A., et al. (2004) J. Cell Biol. 165:813-822 ; Satoh., et al. (2002) Biochem. Biophys. Res. Commun. 291 (5): 1166-72;

NCBI and Uniprot Product Information

• NCBI GI #: 4557317
• NCBI GeneID: 311
• NCBI Accession #: NP_001148
• NCBI GenBank Nucleotide #: NM_001157.2
• UniProt Accession #: P50995; B4DVE7
• Molecular Weight: 56.6kDa (525aa) confirmed by MALDI-TOF
• NCBI Official Full Name: annexin A11 isoform 1
• NCBI Official Synonym Full Names: annexin A11
• NCBI Official Symbol: ANXA11
• NCBI Official Synonym Symbols: ALS23; ANX11; CAP50; CAP-50
• NCBI Protein Information: annexin A11
• UniProt Protein Name: Annexin A11
• Protein Family: Annexin
• UniProt Gene Name: ANXA11
• UniProt Synonym Gene Names: ANX11; CAP-50

NCBI Description

This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq, Dec 2015]

Uniprot Description

Binds specifically to calcyclin in a calcium-dependent manner (). Required for midbody formation and completion of the terminal phase of cytokinesis.