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Synaptobrevin 1 Recombinant Protein | VAMP1 recombinant protein

Synaptobrevin 1, 1-91aa, Human, His tag, E Coli

Gene Names
VAMP1; SYB1; SPAX1; VAMP-1
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
Synaptobrevin 1; 1-91aa; Human; His tag; E Coli; Vesicle-associated membrane protein 1 isoform 1; VAMP1; SYB1; VAMP-1; Synaptobrevin-1; Vesicle-associated membrane protein 1; Vesicle-associated membrane protein 1 isoform 1 DKFZp686H12131; SYB 1; Synaptobrevin1; VAMP 1; Vesicle associated membrane protein 1; Vesicle associated membrane protein 1 synaptobrevin 1.; VAMP1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
In phosphate-buffered saline (pH 7.4), 1mM EDTA
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MSAPAQPPAE GTEGTAPGGG PPGPPPNMTS NRRLQQTQAQ VEEVVDIIRV NVDKVLERDQ KLSELDDRAD ALQAGASQFE SSAAKLKRKY W
Sequence Length
118
Applicable Applications for VAMP1 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

SDS-Page

SDS-Page
Related Product Information for VAMP1 recombinant protein
Synaptobrevin 1 (Vehicle-associated membrane, VAMP1) is one of the key proteins in the SNARE complex which is involved in regulated exocytosis. Synaptobrevin1 binds to t-SNAREs, syntaxin (STX) and SNAP25, after the fusion of synaptic vesicles to plasma membrane. Recombinant human Synaptobrevin1, fused to His- tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for VAMP1 recombinant protein
References
Nystuen AM., et al. (2007) Neurogenetics. 8:1-10.; Pennuto M., et al. (2003) Mol Biol Cell. 14:4909-19.;

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11.9 kDa (111 aa), confirmed by MALDI-TOF.
NCBI Official Full Name
vesicle-associated membrane protein 1 isoform 1
NCBI Official Synonym Full Names
vesicle associated membrane protein 1
NCBI Official Symbol
VAMP1
NCBI Official Synonym Symbols
SYB1; SPAX1; VAMP-1
NCBI Protein Information
vesicle-associated membrane protein 1
UniProt Protein Name
Vesicle-associated membrane protein 1
UniProt Gene Name
VAMP1
UniProt Synonym Gene Names
SYB1; VAMP-1

NCBI Description

Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014]

Uniprot Description

Involved in the targeting and/or fusion of transport vesicles to their target membrane.

Research Articles on VAMP1

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Product Notes

The VAMP1 vamp1 (Catalog #AAA203018) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's Synaptobrevin 1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the VAMP1 vamp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MSAPAQPPAE GTEGTAPGGG PPGPPPNMTS NRRLQQTQAQ VEEVVDIIRV NVDKVLERDQ KLSELDDRAD ALQAGASQFE SSAAKLKRKY W. It is sometimes possible for the material contained within the vial of "Synaptobrevin 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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