Western Blot (WB)
(Western Blot: Sample: Lane1: Mouse Placenta Tissue; Lane2: Human Hela Cells; Lane3: Human K562 Cells; Lane4: Human MCF-7 Cells.)
Rabbit anti-Mouse Annexin A2 Polyclonal Antibody | anti-ANXA2 antibody
Polyclonal Antibody to Annexin A2 (ANXA2)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-VKTKG VDEVTIVNIL TNRSNVQRQD IAFAYQRRTK KELPSALKSA LSGHLETVIL GLLKTPAQYD ASELKASMKG LGTDEDSLIE IICSRTNQEL QEINRVYKEM YKTDLEKDII SDTSGDFRKL MVALAKGRRA E
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Lane1: Mouse Placenta Tissue; Lane2: Human Hela Cells; Lane3: Human K562 Cells; Lane4: Human MCF-7 Cells.)
Western Blot (WB)
(Western Blot: Sample: Lane1: Mouse Placenta Tissue; Lane2: Human Hela Cells; Lane3: Human K562 Cells; Lane4: Human MCF-7 Cells.)
Western Blot (WB)
(Western Blot: Sample: Recombinant ANXA2, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant ANXA2, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Vas Deferens Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Vas Deferens Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Uterus Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Uterus Tissue.)
NCBI and Uniprot Product Information
Uniprot Description
ANXA2: a calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. Heterotetramer containing 2 light chains of S100A10 2 heavy chains of ANXA2. May cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.
Protein type: Calcium-binding; Lipid-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 9 C|9 38.58 cM
Cellular Component: basement membrane; basolateral plasma membrane; cell cortex; cell junction; cell surface; cell-cell adherens junction; cytoplasm; cytosol; early endosome; endosome; extracellular exosome; extracellular matrix; extracellular region; extracellular space; extrinsic component of plasma membrane; late endosome membrane; lipid droplet; lysosomal membrane; macropinosome; membrane; membrane raft; midbody; nucleus; PCSK9-AnxA2 complex; perinuclear region of cytoplasm; plasma membrane; protein complex; proteinaceous extracellular matrix; ruffle; sarcolemma; stress fiber; vesicle
Molecular Function: bone sialoprotein binding; cadherin binding involved in cell-cell adhesion; calcium ion binding; calcium-dependent phospholipid binding; calcium-dependent protein binding; cytoskeletal protein binding; identical protein binding; molecular function regulator; phosphatidylinositol-4,5-bisphosphate binding; phospholipase A2 inhibitor activity; phospholipase inhibitor activity; protease binding; protein binding; Rab GTPase binding; RNA binding; S100 protein binding
Biological Process: angiogenesis; body fluid secretion; catabolism by host of symbiont protein; collagen fibril organization; fibrinolysis; lipid raft formation; membrane budding; negative regulation by host of symbiont molecular function; negative regulation of low-density lipoprotein particle receptor catabolic process; positive regulation of binding; positive regulation of fibroblast proliferation; positive regulation of low-density lipoprotein particle clearance; positive regulation of low-density lipoprotein particle receptor binding; positive regulation of low-density lipoprotein receptor activity; positive regulation of protein phosphorylation; positive regulation of receptor recycling; positive regulation of receptor-mediated endocytosis involved in cholesterol transport; positive regulation of vesicle fusion; protein heterotetramerization; protein localization to plasma membrane
Research Articles on ANXA2
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Product Notes
The ANXA2 anxa2 (Catalog #AAA2027178) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Annexin A2 (ANXA2) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Annexin A2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the ANXA2 anxa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-VKT KG VDEVTIVNIL TNRSNVQRQD IAFAYQRRTK KELPSALKSA LSGHLETVIL GLLKTPAQYD ASELKASMKG LGTDEDSLIE IICSRTNQEL QEINRVYKEM YKTDLEKDII SDTSGDFRKL MVALAKGRRA E. It is sometimes possible for the material contained within the vial of "Annexin A2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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