Related Product Information for MTHFS cdna clone
MTHFS an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5, 10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for MTHFS.
Product Categories/Family for MTHFS cdna clone
NCBI Description
The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Uniprot Description
Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.
Product Notes
The MTHFS mthfs (Catalog #
AAA200780) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Nucleotide Sequence: ATGGCGGCGG CAGCGGTGAG CAGCGCCAAG CGGAGCCTGC GGGGAGAGCT GAAGCAGCGT CTGCGGGCGA TGAGTGCCGA GGAGCGGCTA CGCCAGTCCC GCGTACTGAG CCAGAAGGTG ATTGCCCACA GTGAGTATCA AAAGTCCAAA AGAATTTCCA TCTTTCTGAG CATGCAAGAT GAAATTGAGA CAGAAGAGAT CATCAAGGAC ATTTTCCAAC GAGGCAAAAT CTGCTTCATC CCTCGGTACC GGTTCCAGAG CAATCACATG GATATGGTGA GAATAGAATC ACCAGAGGAA ATTTCTTTAC TTCCCAAAAC ATCCTGGAAT ATCCCTCAGC CTGGTGAGGG TGATGTTCGG GAGGAGGCCT TGTCCACAGG GGGACTTGAT CTCATCTTCA TGCCAGGCCT TGGGTTTGAC AAACATGGCA ACCGACTGGG GAGGGGCAAG GGCTACTATG ATGCCTATCT GAAGCGCTGT TTGCAGCATC AGGAAGTGAA GCCCTACACC CTGGCGTTGG CTTTCAAAGA ACAGATTTGC CTCCAGGTCC CAGTGAATGA AAACGACATG AAGGTAGATG AAGTCCTTTA CGAAGACTCG TCAACAGCTT AA Translatio n Sequence: MAAAAVSSAK RSLRGELKQR LRAMSAEERL RQSRVLSQKV IAHSEYQKSK RISIFLSMQD EIETEEIIKD IFQRGKICFI PRYRFQSNHM DMVRIESPEE ISLLPKTSWN IPQPGEGDVR EEALSTGGLD LIFMPGLGFD KHGNRLGRGK GYYDAYLKRC LQHQEVKPYT LALAFKEQIC LQVPVNENDM KVDEVLYEDS STA.
It is sometimes possible for the material contained within the vial of
"MTHFS, cDNA Clone" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
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