Immunostaining
Rabbit CLAC-P Polyclonal Antibody
CLAC-P Polyclonal Antibody
Applications
Immunoblot, Western Blot, Immunohistochemistry
Synonyms
CLAC-P; Polyclonal Antibody; CLAC-P Polyclonal Antibody; anti-CLAC-P antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
CLAC-P [Rabbit polyclonal antibody to CLAC-P]
This antibody recognizes native and human and mouse CLAC-P.
This antibody recognizes native and human and mouse CLAC-P.
Form/Format
100 ug antigen affinity-purified antibody in PBS, pH 7.4.
Applicable Applications for anti-CLAC-P antibody
Immunoblot, Immunohistochemistry
Application Notes
Immunoblotting: at 2-5ug/ml, a band of approx. 70 kDa is detected in HEK293 cell lysate.
Immunohistochemistry (paraffin): at 5-10ug/ml, positive staining of senile plaques in AD brains.
These are recommended concen-trations. User should determine optimal concentrations for their applications.
Immunohistochemistry (paraffin): at 5-10ug/ml, positive staining of senile plaques in AD brains.
These are recommended concen-trations. User should determine optimal concentrations for their applications.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Immunostaining
Immunostaining
Related Product Information for anti-CLAC-P antibody
Alzheimer's disease (AD) is characterized by deposition of beta -amyloid as senile plaques and cerebral amyloid angiopathy. The principal component of AD amyloid is the amyloid beta peptide (A beta ). Although production and deposition of A beta appear closely related to the pathogenesis of AD, current evidence suggest that A beta alone is not sufficient to cause neuronal death and symptoms of dementia. A component of senile plaque (SP), CLAC (collagen-like Alzheimer amyloid plaque component ) and its precursor CLAC-P are deposited with extracellular beta -amyloid and have been recently implicated in cell toxicity of beta -amyloid in AD brains. CLAC-P is a unique, membrane-bound collagen-like structure containing three Gly-X-Y repeat motifs and may define a novel class of neuronal collagens.
Product Categories/Family for anti-CLAC-P antibody
Similar Products
Product Notes
The CLAC-P (Catalog #AAA194432) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CLAC-P can be used in a range of immunoassay formats including, but not limited to, Immunoblot, Immunohistochemistry. Immunoblotting: at 2-5ug/ml, a band of approx. 70 kDa is detected in HEK293 cell lysate. Immunohistochemistry (paraffin): at 5-10ug/ml, positive staining of senile plaques in AD brains. These are recommended concen-trations. User should determine optimal concentrations for their applications. Researchers should empirically determine the suitability of the CLAC-P for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLAC-P, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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