Rabbit DcR1 (ED2) Antibody | anti-Dcr-1 antibody
Anti-DcR1 (ED2) Antibody
Gene Names
Dcr-1; cg4792; CG4792; Dcr; dcr 1; dcr-1; dcr1; Dcr1; DCR1; dicer; Dicer; DICER; dicer-1; dicer1; Dicer1; DmelCG4792
Applications
Immunoblot, Western Blot
Synonyms
DcR1 (ED2); Anti-DcR1 (ED2) Antibody; Anti-DcR1 (ED2); anti-Dcr-1 antibody
Host
Rabbit
Specificity
Anti-DcR1 (ED2) [Rabbit antibody to peptide corresponding to aa 111-123 in the extracellular domain of human DcR1 precursor.]
This antibody recognizes human, mouse, and rat DcR1 (65 kD).
This antibody recognizes human, mouse, and rat DcR1 (65 kD).
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Applicable Applications for anti-Dcr-1 antibody
Immunoblot
Application Notes
Immunoblotting: use at 1:500-1:1,000 dilution.
Positive control: Whole cell lysate from HeLa cells.
Positive control: Whole cell lysate from HeLa cells.
Antigen
Peptide corresponding to aa 111-123 at the extracellular domain (ED) of human DcR1 precursor.
Stabilizer
None
Preservatives
0.02% sodium azide.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-Dcr-1 antibody
Apoptosis is induced by certain cytokines including TNF and Fas ligand through their death domain-containing receptors. TRAIL/Apo2L is a new member of the TNF family that induces apoptosis in a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has an extracellular TRAIL-binding domain but lacks an intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts are expessed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 does not induce apoptosis but attenuates TRAILinduced apoptosis.
Product Categories/Family for anti-Dcr-1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
Dicer-1
NCBI Official Synonym Full Names
Dicer-1
NCBI Official Symbol
Dcr-1
NCBI Official Synonym Symbols
cg4792; CG4792; Dcr; dcr 1; dcr-1; dcr1; Dcr1; DCR1; dicer; Dicer; DICER; dicer-1; dicer1; Dicer1; DmelCG4792
NCBI Protein Information
CG4792 gene product from transcript CG4792-RA; Dicer-1; CG4792-PA; Dcr-1-PA; Dicer1; dicer
Protein Family
Research Articles on Dcr-1
Similar Products
Product Notes
The Dcr-1 (Catalog #AAA194059) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DcR1 (ED2) can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting: use at 1:500-1:1,000 dilution. Positive control: Whole cell lysate from HeLa cells. Researchers should empirically determine the suitability of the Dcr-1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DcR1 (ED2), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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