Western Blot (WB)
(Anti- Prolactin Picoband antibody, MBS177988, Western blottingAll lanes: Anti Prolactin (MBS177988) at 0.5ug/mlWB: Recombinant Mouse Prolactin Protein 0.5ngPredicted bind size: 10KDObserved bind size: 10KD )
anti-Mouse Prolactin Polyclonal Antibody | anti-Prl antibody
Anti-Prolactin Antibody
Gene Names
Prl; Gha1; Prl1a1; AV290867
Reactivity
Mouse
Applications
Western Blot, ELISA
Purity
Immunogen Affinity Purified
Synonyms
Prolactin; Polyclonal Antibody; Anti-Prolactin Antibody; Decidual prolactin; Lactogenic Hormone; Luteotropic Hormone; Mammotropin; PRL; Prolactin precursor; prolactin; anti-Prl antibody
Reactivity
Mouse
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
226
Applicable Applications for anti-Prl antibody
Western Blot (WB), ELISA (EIA)
Application Notes
ELISA Concentration: 0.1-0.5ug/ml
Western Blot Concentration: 0.1-0.5ug/ml
Western Blot Concentration: 0.1-0.5ug/ml
Immunogen
E Coli-derived mouse Prolactin recombinant protein (Position: L30-C226). Mouse Prolactin shares 59.8% and 84.8% amino acid (aa) sequence identity with human and rat Prolactin, respectively.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Western Blot (WB)
(Anti- Prolactin Picoband antibody, MBS177988, Western blottingAll lanes: Anti Prolactin (MBS177988) at 0.5ug/mlWB: Recombinant Mouse Prolactin Protein 0.5ngPredicted bind size: 10KDObserved bind size: 10KD )
Western Blot (WB)
(Anti- Prolactin Picoband antibody, MBS177988, Western blottingAll lanes: Anti Prolactin (MBS177988) at 0.5ug/mlWB: Recombinant Mouse Prolactin Protein 0.5ngPredicted bind size: 10KDObserved bind size: 10KD )
Related Product Information for anti-Prl antibody
Description: Rabbit IgG polyclonal antibody for Prolactin(PRL) detection. Tested with WB, ELISA in Mouse.
Background: Prolactin (PRL) also known as luteotropic hormone (LTH) is a protein that in humans is encoded by the PRL gene. Prolactin is a peptide hormone discovered by Henry Friesen. Although it is perhaps best known for its role in lactation, prolactin already existed in the oldest known vertebrates-fishes-where its most important functions were probably related to control of water and salt balance. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. Prolactin has important cell cycle related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor binding to cytokine like receptors it has also profound influence on hematopoiesis, angiogenesis and is involved in the regulation of blood clotting through several pathways.
Background: Prolactin (PRL) also known as luteotropic hormone (LTH) is a protein that in humans is encoded by the PRL gene. Prolactin is a peptide hormone discovered by Henry Friesen. Although it is perhaps best known for its role in lactation, prolactin already existed in the oldest known vertebrates-fishes-where its most important functions were probably related to control of water and salt balance. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. Prolactin has important cell cycle related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor binding to cytokine like receptors it has also profound influence on hematopoiesis, angiogenesis and is involved in the regulation of blood clotting through several pathways.
References
1. Cooke, N. E., Baxter, J. D.Structural analysis of the prolactin gene suggests a separate origin for its 5-prime end.Nature 297: 603-606, 1982. 2. Ling, C., Svensson, L., Oden, B., Weijdegard, B., Eden, B., Eden, S., Billig, H.Identification of functional prolactin (PRL) receptor gene expression: PRL inhibits lipoprotein lipase activity in human white adipose tissue.J. Clin. Endocr. Metab. 88: 1804-1808, 2003. 3. Shingo, T., Gregg, C., Enwere, E., Fujikawa, H., Hassam, R., Geary, C., Cross, J. C., Weiss, S.Pregnancy-stimulated neurogenesis in the adult female forebrain mediated by prolactin. Science 299: 117-120, 2003.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
25,496 Da
NCBI Official Full Name
Prolactin
NCBI Official Synonym Full Names
prolactin
NCBI Official Symbol
Prl
NCBI Official Synonym Symbols
Gha1; Prl1a1; AV290867
NCBI Protein Information
prolactin
UniProt Protein Name
Prolactin
Protein Family
UniProt Gene Name
Prl
UniProt Synonym Gene Names
PRL
UniProt Entry Name
PRL_MOUSE
Uniprot Description
prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.
Protein type: Cytokine; Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis
Cellular Component: extracellular region; secretory granule
Molecular Function: hormone activity; prolactin receptor binding
Biological Process: lactation; mammary gland development; maternal behavior; positive regulation of cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of JAK-STAT cascade; regulation of JAK-STAT cascade; regulation of ossification; STAT protein nuclear translocation
Research Articles on Prl
Similar Products
Product Notes
The Prl prl (Catalog #AAA177988) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Prolactin Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Prolactin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). ELISA Concentration: 0.1-0.5ug/ml Western Blot Concentration: 0.1-0.5ug/ml. Researchers should empirically determine the suitability of the Prl prl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Prolactin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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