Western Blot (WB)
(Anti-HSPA2 antibody, MBS176190, Western blottingLane 1: Rat Testis Tissue LysateLane 2: A549 Cell LysateLane 3: MCF-7 Cell LysateLane 4: HELA Cell Lysate )
Rabbit HSPA2 Polyclonal Antibody | anti-HSPA2 antibody
Anti-HSPA2 antibody
Gene Names
HSPA2; HSP70-2; HSP70-3
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Immunogen affinity purified.
Synonyms
HSPA2; Polyclonal Antibody; Anti-HSPA2 antibody; Heat shock-related 70 kDa protein 2; heat shock 70kDa protein 2; 70kDa antibody; DAQB 147D11.1 001 antibody; Hcp70.2 antibody; Heat shock 70 kDa protein 2 antibody; heat shock 70kDa protein 1A antibody; Heat shock protein 2 antibody; heat shock protein 70 antibody; Heat shock protein 70.2 antibody; Heat shock related 70 kDa protein 2 antibody; Heat shock-related 70 kDa protein 2 antibody; Heat-shock protein; 70-KD; 2 antibody; 3 antibody; HSP70 2 antibody; HSP70 3 antibody; Hsp70-2 antibody; HSP70-3 antibody; HSP70.2 antibody; HSP70A2 antibody; HSP72 antibody; HSP72_HUMAN antibody; HSPA2 antibody; Hspt70 antibody; Hst70 antibody; MGC58299 antibody; MGC7795 antibody; MGC93458 antibody; OTTHUMP00000180664 antibody; Testis-specific heat shock protein-related antibody; XXbac BCX40G17.3 001 antibody; anti-HSPA2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
639
Applicable Applications for anti-HSPA2 antibody
Western Blot (WB)
Immunogen
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human HSPA2 (580-599aa VINWLDRNQMAEKDEYEHKQ), identical to the related mouse and rat sequences.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Western Blot (WB)
(Anti-HSPA2 antibody, MBS176190, Western blottingLane 1: Rat Testis Tissue LysateLane 2: A549 Cell LysateLane 3: MCF-7 Cell LysateLane 4: HELA Cell Lysate )
Western Blot (WB)
(Anti-HSPA2 antibody, MBS176190, Western blottingLane 1: Rat Testis Tissue LysateLane 2: A549 Cell LysateLane 3: MCF-7 Cell LysateLane 4: HELA Cell Lysate )
Related Product Information for anti-HSPA2 antibody
Description: Rabbit IgG polyclonal antibody for Heat shock-related 70 kDa protein 2(HSPA2) detection. Tested with WB in Human, Mouse, Rat.
Background: HSPA2(heat shock 70kDa protein 2) also known as HEAT-SHOCK PROTEIN, 70-KD, 2, HSP70-2, HEAT-SHOCK PROTEIN, 70-KD, 3 or HSP70-3. Analysis of the sequence indicated that HSPA2 is the human homolog of the murine Hsp70-2 gene, with 91.7% identity in the nucleotide coding sequence and 98.2% in the corresponding amino acid sequence.HSPA2 has less amino acid homology to the other members of the human HSP70 gene family. HSPA2 is constitutively expressed in most tissues, with very high levels in testis and skeletal muscle. The HSPA2 gene is located on chromosome 14q22-q24. Immunohistochemical analysis detected weak expression of HSPA2 in spermatocytes and stronger expression in spermatids and in the tail of mature sperm. HSPA2 may be critical to sperm maturation through its role as a protein chaperone.
Background: HSPA2(heat shock 70kDa protein 2) also known as HEAT-SHOCK PROTEIN, 70-KD, 2, HSP70-2, HEAT-SHOCK PROTEIN, 70-KD, 3 or HSP70-3. Analysis of the sequence indicated that HSPA2 is the human homolog of the murine Hsp70-2 gene, with 91.7% identity in the nucleotide coding sequence and 98.2% in the corresponding amino acid sequence.HSPA2 has less amino acid homology to the other members of the human HSP70 gene family. HSPA2 is constitutively expressed in most tissues, with very high levels in testis and skeletal muscle. The HSPA2 gene is located on chromosome 14q22-q24. Immunohistochemical analysis detected weak expression of HSPA2 in spermatocytes and stronger expression in spermatids and in the tail of mature sperm. HSPA2 may be critical to sperm maturation through its role as a protein chaperone.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
70,021 Da
NCBI Official Full Name
Heat shock-related 70 kDa protein 2
NCBI Official Synonym Full Names
heat shock 70kDa protein 2
NCBI Official Symbol
HSPA2
NCBI Official Synonym Symbols
HSP70-2; HSP70-3
NCBI Protein Information
heat shock-related 70 kDa protein 2; heat shock 70kD protein 2
UniProt Protein Name
Heat shock-related 70 kDa protein 2
Protein Family
UniProt Gene Name
HSPA2
UniProt Synonym Gene Names
Heat shock 70 kDa protein 2
UniProt Entry Name
HSP72_HUMAN
Uniprot Description
HSPA2: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Interacts with ZNF541. Component of the CatSper complex. Belongs to the heat shock protein 70 family.
Protein type: Heat shock protein; Chaperone
Chromosomal Location of Human Ortholog: 14q24.1
Cellular Component: male germ cell nucleus; cell surface; mitochondrion; membrane; synaptonemal complex; nucleus; cytosol
Molecular Function: protein binding; enzyme binding; unfolded protein binding; glycolipid binding; ATP binding
Biological Process: G2/M-specific positive regulation of cyclin-dependent protein kinase activity; male meiosis I; protein refolding; male meiosis; response to unfolded protein; spermatid development
Research Articles on HSPA2
Similar Products
Product Notes
The HSPA2 hspa2 (Catalog #AAA176190) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-HSPA2 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HSPA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the HSPA2 hspa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSPA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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