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Western Blot (WB) (Western blot analysis of HSPA2 on different lysates using anti-HSPA2 antibody at 1/1, 000 dilution. Positive control: Lane 1: MCF-7 Lane 2: Hela Lane 3: A431)

Rabbit HSPA2 Monoclonal Antibody | anti-HSPA2 antibody

HSPA2 Antibody

Gene Names
HSPA2; HSP70-2; HSP70-3
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
ProA affinity purified
Synonyms
HSPA2; Monoclonal Antibody; HSPA2 Antibody; 70kDa antibody; Hcp70.2 antibody; Heat shock 70 kDa protein 2 antibody; Heat shock protein 2 antibody; Heat shock protein 70.2 antibody; Heat shock related 70 kDa protein 2 antibody; Heat shock-related 70 kDa protein 2 antibody; Heat-shock protein; 70-KD; 2 antibody; 3 antibody; HSP70 2 antibody; HSP70 3 antibody; Hsp70-2 antibody; HSP70-3 antibody; HSP70.2 antibody; HSP70A2 antibody; HSP72 antibody; HSP72_HUMAN antibody; HSPA2 antibody; Hspt70 antibody; Hst70 antibody; MGC58299 antibody; MGC7795 antibody; MGC93458 antibody; OTTHUMP00000180664 antibody; Testis-specific heat shock protein-related antibody; anti-HSPA2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
JJ08-77
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-HSPA2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:1000-1:2000
IHC: 1:50-1:200
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.

Western Blot (WB)

(Western blot analysis of HSPA2 on different lysates using anti-HSPA2 antibody at 1/1, 000 dilution. Positive control: Lane 1: MCF-7 Lane 2: Hela Lane 3: A431)

Western Blot (WB) (Western blot analysis of HSPA2 on different lysates using anti-HSPA2 antibody at 1/1, 000 dilution. Positive control: Lane 1: MCF-7 Lane 2: Hela Lane 3: A431)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-HSPA2 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-HSPA2 antibody. Counter stained with hematoxylin.)
Related Product Information for anti-HSPA2 antibody
HSPA2 (heat shock 70kDa protein 2) also known as HEAT-SHOCK PROTEIN, 70-KD, 2, HSP70-2, HEAT-SHOCK PROTEIN, 70-KD, 3 or HSP70-3. Analysis of the sequence indicated that HSPA2 is the human homolog of the murine Hsp70-2 gene, with 91.7% identity in the nucleotide coding sequence and 98.2% in the corresponding amino acid sequence.HSPA2 has less amino acid homology to the other members of the human HSP70 gene family. HSPA2 is constitutively expressed in most tissues, with very high levels in testis and skeletal muscle. The HSPA2 gene is located on chromosome 14q22-q24. Immunohistochemical analysis detected weak expression of HSPA2 in spermatocytes and stronger expression in spermatids and in the tail of mature sperm. HSPA2 may be critical to sperm maturation through its role as a protein chaperone.
Product Categories/Family for anti-HSPA2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
70,021 Da
NCBI Official Full Name
Heat shock-related 70 kDa protein 2
NCBI Official Synonym Full Names
heat shock 70kDa protein 2
NCBI Official Symbol
HSPA2
NCBI Official Synonym Symbols
HSP70-2; HSP70-3
NCBI Protein Information
heat shock-related 70 kDa protein 2; heat shock 70kD protein 2
UniProt Protein Name
Heat shock-related 70 kDa protein 2
UniProt Gene Name
HSPA2
UniProt Synonym Gene Names
Heat shock 70 kDa protein 2
UniProt Entry Name
HSP72_HUMAN

Uniprot Description

HSPA2: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Interacts with ZNF541. Component of the CatSper complex. Belongs to the heat shock protein 70 family.

Protein type: Heat shock protein; Chaperone

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: male germ cell nucleus; cell surface; mitochondrion; membrane; synaptonemal complex; nucleus; cytosol

Molecular Function: protein binding; enzyme binding; unfolded protein binding; glycolipid binding; ATP binding

Biological Process: G2/M-specific positive regulation of cyclin-dependent protein kinase activity; male meiosis I; protein refolding; male meiosis; response to unfolded protein; spermatid development

Research Articles on HSPA2

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Product Notes

The HSPA2 hspa2 (Catalog #AAA9435982) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HSPA2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HSPA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:1000-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the HSPA2 hspa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSPA2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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