Rabbit DNAJA2 Polyclonal Antibody | anti-DNAJA2 antibody

Anti-DNAJA2 Antibody

Cat. Num. AAA1753168

• Gene Names: DNAJA2; DJ3; CPR3; DJA2; DNAJ; DNJ3; RDJ2; HIRIP4; PRO3015
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay, ELISA
• Purity: Immunogen affinity purified.
• Synonyms: DNAJA2; Polyclonal Antibody; Anti-DNAJA2 Antibody; DnaJ homolog subfamily A member 2; Cell cycle progression restoration gene 3 protein; Dnj3; Dj3; HIRA-interacting protein 4; Renal carcinoma antigen NY-REN-14; CPR3; HIRIP4; anti-DNAJA2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: No cross reactivity with other proteins.
• Purity/Purification: Immunogen affinity purified.
• Form/Format: Lyophilized; Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Sequence Length: 412

• Applicable Applications for anti-DNAJA2 antibody: Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Flow Cytometry (FC/FACS), Direct ELISA (EIA)
• Application Notes: WB: 0.25-0.5ug/ml (Human, Mouse, Rat); IHC-P (Embedded Section): 0.5-1ug/ml (Human, Mouse, Rat); FC/FACS: 1-3ug/1x106 cells (Human, Mouse, Rat); Direct ELISA: 0.1-0.5ug/ml (Human); Tested Species: In-house tested species with positive results.
• Immunogen: E Coli-derived human DNAJA2 recombinant protein (Position: M1-N140).
• Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
• Preparation and Storage: Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen store at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Related Product Information for anti-DNAJA2 antibody

Description: Rabbit IgG polyclonal antibody for DNAJA2 detection. Tested with WB, IHC-P, FCM, Direct ELISA in Human; Mouse; Rat.

Background: DnaJ homolog subfamily A member 2 is a protein that in humans is encoded by the DNAJA2 gene. It is mapped to 16q11.2. The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro.

References

1. Edwards, M. C., Liegeois, N., Horecka, J., DePinho, R. A., Sprague, G. F., Jr., Tyers, M., Elledge, S. J. Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells. Genetics 147: 1063-1076, 1997.
2. Ohtsuka, K., Hata, M. Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. Cell Stress Chaperones 5: 98-112, 2000.
3. Terada, K., Yomogida, K., Imai, T., Kiyonari, H., Takeda, N., Kadomatsu, T., Yano, M., Aizawa, S., Mori, M. A type I DnaJ homolog, DjA1, regulates androgen receptor signaling and spermatogenesis. EMBO J. 24: 611-622, 2005.

NCBI and Uniprot Product Information

• NCBI GI #: 5031741
• NCBI GeneID: 10294
• NCBI Accession #: NP_005871
• NCBI GenBank Nucleotide #: NP_005871.1
• UniProt Accession #: O60884
• NCBI Official Full Name: dnaJ homolog subfamily A member 2
• NCBI Official Synonym Full Names: DnaJ heat shock protein family (Hsp40) member A2
• NCBI Official Symbol: DNAJA2
• NCBI Official Synonym Symbols: DJ3; CPR3; DJA2; DNAJ; DNJ3; RDJ2; HIRIP4; PRO3015
• NCBI Protein Information: dnaJ homolog subfamily A member 2
• UniProt Protein Name: DnaJ homolog subfamily A member 2
• Protein Family: DnaJ homolog subfamily
• UniProt Gene Name: DNAJA2
• UniProt Synonym Gene Names: CPR3; HIRIP4; Dj3
• UniProt Entry Name: DNJA2_HUMAN

NCBI Description

The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. [provided by RefSeq, Jul 2008]