Rabbit DNAJA2 Polyclonal Antibody | anti-DNAJA2 antibody
DNAJA2 Antibody (N-term)
evolutionarily conserved DNAJ/HSP40 family of proteins, which
regulate molecular chaperone activity by stimulating ATPase
activity. DNAJ proteins may have up to 3 distinct domains: a
conserved 70-amino acid J domain, usually at the N terminus; a
glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain
containing 4 motifs resembling a zinc finger domain. The product of
this gene works as a cochaperone of Hsp70s in protein folding and
mitochondrial protein import in vitro.
Rosales-Hernandez, A., et al. Cell Stress Chaperones 14(1):71-82(2009)
Tzankov, S., et al. J. Biol. Chem. 283(40):27100-27109(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. [provided by RefSeq, Jul 2008]
Uniprot Description
DNAJA2: Co-chaperone of Hsc70.
Protein type: Chaperone; Cell cycle regulation
Chromosomal Location of Human Ortholog: 16q12.1
Cellular Component: membrane; cytosol
Molecular Function: protein binding; heat shock protein binding; metal ion binding; chaperone binding; unfolded protein binding; ATP binding
Biological Process: response to heat; positive regulation of cell proliferation; protein refolding
Research Articles on DNAJA2
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Product Notes
The DNAJA2 dnaja2 (Catalog #AAA9214698) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 44-72. The DNAJA2 Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's DNAJA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the DNAJA2 dnaja2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNAJA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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