Immunohistochemistry (IHC)
(Anti-Thrombospondin 2 antibody, MBS175301, IHC(P)IHC(P): Human Placenta Tissue )
Rabbit anti-Human Thrombospondin 2 Polyclonal Antibody | anti-THBS2 antibody
Anti-Thrombospondin 2 antibody
Immunohistochemistry (IHC)
(Anti-Thrombospondin 2 antibody, MBS175301, IHC(P)IHC(P): Human Placenta Tissue )
Immunohistochemistry (IHC)
(Anti-Thrombospondin 2 antibody, MBS175301, IHC(P)IHC(P): Human Placenta Tissue )
Western Blot (WB)
(Anti-Thrombospondin 2 antibody, MBS175301, Western blottingAll lanes: Anti THBS2 (MBS175301) at 0.5ug/mlLane 1: SMMC Whole Cell Lysate at 40ugLane 2: MCF-7 Whole Cell Lysate at 40ugLane 3: HT1080 Whole Cell Lysate at 40ugLane 4: JURKAT Whole Cell Lysate at 40ugLane 5: NIH 3T3 Whole Cell Lysate at 40ugPredicted bind size: 130KDObserved bind size: 130KD )
Western Blot (WB)
(Anti-Thrombospondin 2 antibody, MBS175301, Western blottingAll lanes: Anti THBS2 (MBS175301) at 0.5ug/mlLane 1: SMMC Whole Cell Lysate at 40ugLane 2: MCF-7 Whole Cell Lysate at 40ugLane 3: HT1080 Whole Cell Lysate at 40ugLane 4: JURKAT Whole Cell Lysate at 40ugLane 5: NIH 3T3 Whole Cell Lysate at 40ugPredicted bind size: 130KDObserved bind size: 130KD )
Background: Thrombospondin-2(THBS2) is a protein that in humans is encoded by the THBS2 gene. The protein encoded by this gene belongs to the thrombospondin family. The THBS2 is mapped to 6q27 and it is located on chromosome 17. The gene was transcribed in fibroblasts, smooth muscle cells, and an osteosarcoma cell line. It functions as a protein inhibitor of tumor growth and angiogenesis and modulates the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration. [provided by RefSeq, Jul 2008]
Uniprot Description
THBS2: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. Genetic variations in THBS2 may be a cause of susceptibility to intervertebral disk disease (IDD); also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain. Belongs to the thrombospondin family.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 6q27
Cellular Component: extracellular region; basement membrane
Molecular Function: heparin binding; protein binding; calcium ion binding
Biological Process: positive regulation of synaptogenesis; negative regulation of angiogenesis; cell adhesion
Disease: Intervertebral Disc Disease
Research Articles on THBS2
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Product Notes
The THBS2 thbs2 (Catalog #AAA175301) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Thrombospondin 2 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Thrombospondin 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the THBS2 thbs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thrombospondin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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