Rabbit anti-Human AVPR1A/V1aR Polyclonal Antibody | anti-AVPR1A/V1aR antibody
Anti-AVPR1A/V1aR Antibody
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Direct ELISA: 0.1-0.5ug/mL
Tested Species: In-house tested species with positive results. Other applications have not been tested.
Background: Arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types for arginine vasopressin (AVPR1B and AVPR2 being the others). It belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. This gene is mapped to 12q14.2. AVPR1A is present throughout the brain, as well as in the periphery, in the liver, kidney, and vasculature. The protein encoded by this gene acts as receptor for arginine vasopressin. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]
Uniprot Description
AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 12q14-q15
Cellular Component: integral to plasma membrane; plasma membrane; cytoplasmic vesicle; endosome
Molecular Function: protein binding; protein kinase C binding; V1A vasopressin receptor binding; peptide hormone binding; peptide binding; vasopressin receptor activity
Biological Process: blood circulation; positive regulation of glutamate secretion; positive regulation of cellular pH reduction; positive regulation of systemic arterial blood pressure; cellular response to water deprivation; elevation of cytosolic calcium ion concentration; positive regulation of cell proliferation; response to corticosterone stimulus; penile erection; positive regulation of prostaglandin biosynthetic process; grooming behavior; generation of precursor metabolites and energy; maternal behavior; myotube differentiation; calcium-mediated signaling; positive regulation of heart rate; social behavior; positive regulation of cell growth; cellular response to hormone stimulus; negative regulation of female receptivity; G-protein coupled receptor protein signaling pathway; telencephalon development; negative regulation of transmission of nerve impulse; regulation of systemic arterial blood pressure by vasopressin; phospholipase C activation; positive regulation of vasoconstriction; sperm ejaculation
Research Articles on AVPR1A/V1aR
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Product Notes
The AVPR1A/V1aR avpr1a (Catalog #AAA1752869) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-AVPR1A/V1aR Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AVPR1A/V1aR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Direct ELISA (EIA). WB: 0.25-0.5ug/mL Direct ELISA: 0.1-0.5ug/mL Tested Species: In-house tested species with positive results. Other applications have not been tested. Researchers should empirically determine the suitability of the AVPR1A/V1aR avpr1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AVPR1A/V1aR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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