Western Blot (WB)
(Western blot analysis of CD80 in EL4 cell lysate with CD80 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Human, Mouse CD80 Polyclonal Antibody | anti-CD80 antibody
CD80 Antibody
The immunogen is located within amino acids 60 - 110 of CD80.
As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of CD80 in EL4 cell lysate with CD80 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of CD80 in EL4 cell lysate with CD80 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Immunofluorescence (IF)
(Immunofluorescence of CD80 in human tonsil tissue with CD80 antibody at 20 μg/ml.Red: CD80 Antibody (8679)Blue: DAPI staining)
Immunofluorescence (IF)
(Immunofluorescence of CD80 in human tonsil tissue with CD80 antibody at 20 μg/ml.Red: CD80 Antibody (8679)Blue: DAPI staining)
NCBI and Uniprot Product Information
Observed: 50 kDa
NCBI Description
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
Uniprot Description
CD80: Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
Protein type: Immunoglobulin superfamily; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q13.33
Cellular Component: cell surface; integral to membrane; plasma membrane
Molecular Function: phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding
Biological Process: cell-cell signaling; phosphoinositide-mediated signaling; positive regulation of peptidyl-tyrosine phosphorylation; regulation of phosphoinositide 3-kinase cascade; T cell activation; T cell costimulation
Research Articles on CD80
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Product Notes
The CD80 cd80 (Catalog #AAA154467) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD80 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD80 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the CD80 cd80 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD80, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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