Western Blot (WB)
(Western blot analysis of DELE in rat brain tissue lysate with DELE antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Human, Rat DELE Polyclonal Antibody | anti-KIAA0141 antibody
DELE Antibody
Gene Names
KIAA0141; DELE
Reactivity
Human, Rat
Applications
ELISA, Western Blot, Immunofluorescence
Purity
DELE Antibody is affinity chromatography purified via peptide column.
Synonyms
DELE; Polyclonal Antibody; DELE Antibody; Death ligand signal enhancer; KIAA0141; anti-KIAA0141 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
DELE Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
515
Applicable Applications for anti-KIAA0141 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes
DELE antibody can be used for detection of DELE by Western blot at 1 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
DELE antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DELE.
Buffer
DELE Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
DELE antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of DELE in rat brain tissue lysate with DELE antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of DELE in rat brain tissue lysate with DELE antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Immunofluorescence (IF)
(Immunofluorescence of DELE in human brain tissue with DELE antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of DELE in human brain tissue with DELE antibody at 20 μg/mL.)
Related Product Information for anti-KIAA0141 antibody
DELE Antibody: DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-α and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-α, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,920 Da
NCBI Official Full Name
death ligand signal enhancer
NCBI Official Synonym Full Names
KIAA0141
NCBI Official Symbol
KIAA0141
NCBI Official Synonym Symbols
DELE
NCBI Protein Information
death ligand signal enhancer
UniProt Protein Name
Death ligand signal enhancer
Protein Family
UniProt Gene Name
KIAA0141
UniProt Synonym Gene Names
DELE
UniProt Entry Name
DELE_HUMAN
Uniprot Description
KIAA0141: Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation.
Chromosomal Location of Human Ortholog: 5q31.3
Cellular Component: mitochondrion
Molecular Function: protein binding
Biological Process: induction of apoptosis via death domain receptors; regulation of caspase activity
Research Articles on KIAA0141
Similar Products
Product Notes
The KIAA0141 kiaa0141 (Catalog #AAA151106) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DELE Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DELE can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). DELE antibody can be used for detection of DELE by Western blot at 1 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the KIAA0141 kiaa0141 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DELE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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