Ubiquitin Carboxyl-Terminal Esterase L1 Active Protein | mUCHL1 active protein
Recombinant Mouse Ubiquitin Carboxyl-Terminal Esterase L1, Active
Gene Names
Uchl1; gad; C88048; PGP9.5; R75593; UCH-L1; UCHL-1; PGP 9.5; AW822034
Purity
Greater than 90.0% as determined by SDS-PAGE
Synonyms
Ubiquitin Carboxyl-Terminal Esterase L1; Recombinant Mouse Ubiquitin Carboxyl-Terminal Esterase L1; Active; Ubiquitin carboxyl-terminal hydrolase isozyme L1; UCH-L1; Neuron cytoplasmic protein 9.5; PGP 9.5; PGP9.5; Ubiquitin thioesterase L1; UCHL1 Mouse; Ubiquitin Carboxyl-Terminal Esterase L1 Mouse Recombinant; mUCHL1 active protein
Host
Escherichia Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE
Form/Format
Sterile filtered colorless solution
Protein solution (1mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT
Protein solution (1mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT
Sequence
MGSSHHHHHH SSGLVPRGSH MGS MQLKPME INPEMLNKVL AKLGVAGQWR FADVLGLEEE TLGSVPSPAC ALLLLFPLTA QHENFRKKQI EELKGQEVSP KVYFMKQTIG NSCGTIGLIH AVANNQDKLE FEDGSVLKQF LSETEKLSPE DRAKCFEKNE AIQAAHDSVA QEGQCRVDDK VNFHFILFNN VDGHLYELDG RMPFPVNHGA SSEDSLLQDA AKVCREFTER EQGEVRFSAV ALCKAA
Sequence Length
223
Biological Activity
Specific activity is > 70 pmol/min/ug, and is defined as the amount of enzyme that hydrolysis 1.0 pmole of ubiquitin-AMC per minute at pH 7.5, at 37 degree C
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles
Related Product Information for mUCHL1 active protein
Description: UCHL1 Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 246 amino acids (1-223 a.a) and having a molecular mass of 27.2kDa. UCHL1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: UbiquitinCarboxyl-Terminal Esterase L1 (UCHL1) is a part of a family whose productshydrolyze small C-terminal adducts of ubiquitin to create the ubiquitin monomer.UCHL1 is a part of the ubiquitin system, which regulates many biologicalactivities. UCHL1 is a thiol protease that distinguishes and hydrolyzes apeptide bond at the C-terminal glycine of ubiquitin. UCHL1 binds to free monoubiquitinand avoids its degradation in lysosomes.
Introduction: UbiquitinCarboxyl-Terminal Esterase L1 (UCHL1) is a part of a family whose productshydrolyze small C-terminal adducts of ubiquitin to create the ubiquitin monomer.UCHL1 is a part of the ubiquitin system, which regulates many biologicalactivities. UCHL1 is a thiol protease that distinguishes and hydrolyzes apeptide bond at the C-terminal glycine of ubiquitin. UCHL1 binds to free monoubiquitinand avoids its degradation in lysosomes.
Product Categories/Family for mUCHL1 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
24,838 Da
NCBI Official Full Name
Ubiquitin carboxyl-terminal hydrolase isozyme L1
NCBI Official Synonym Full Names
ubiquitin carboxy-terminal hydrolase L1
NCBI Official Symbol
Uchl1
NCBI Official Synonym Symbols
gad; C88048; PGP9.5; R75593; UCH-L1; UCHL-1; PGP 9.5; AW822034
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase isozyme L1
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase isozyme L1
UniProt Gene Name
Uchl1
UniProt Synonym Gene Names
UCH-L1; PGP9.5
Uniprot Description
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
Research Articles on mUCHL1
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Product Notes
The mUCHL1 uchl1 (Catalog #AAA147213) is an Active Protein produced from Escherichia Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGS MQLKPME INPEMLNKVL AKLGVAGQWR FADVLGLEEE TLGSVPSPAC ALLLLFPLTA QHENFRKKQI EELKGQEVSP KVYFMKQTIG NSCGTIGLIH AVANNQDKLE FEDGSVLKQF LSETEKLSPE DRAKCFEKNE AIQAAHDSVA QEGQCRVDDK VNFHFILFNN VDGHLYELDG RMPFPVNHGA SSEDSLLQDA AKVCREFTER EQGEVRFSAV ALCKAA. It is sometimes possible for the material contained within the vial of "Ubiquitin Carboxyl-Terminal Esterase L1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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