Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer using DLAT Polyclonal Antibody at dilution of 1/30)
Rabbit DLAT Polyclonal Antibody | anti-DLAT antibody
DLAT Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
DLAT; Polyclonal Antibody; DLAT Polyclonal Antibody; DLTA; PDCE2; PDC-E2; anti-DLAT antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Concentration
3.4mg/ml (varies by lot)
Sequence Length
553
Applicable Applications for anti-DLAT antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:1000-2000
IHC: 1:25-100
WB: 1:200-1000
IHC: 1:25-100
WB: 1:200-1000
Immunogen
Fusion protein of human DLAT
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-166899 / sc-365276
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer using DLAT Polyclonal Antibody at dilution of 1/30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer using DLAT Polyclonal Antibody at dilution of 1/30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer using DLAT Polyclonal Antibody at dilution of 1/30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer using DLAT Polyclonal Antibody at dilution of 1/30)
Related Product Information for anti-DLAT antibody
This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
69 kDa
NCBI Official Full Name
DlaT
Similar Products
Product Notes
The DLAT (Catalog #AAA2542620) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DLAT Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DLAT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-2000 IHC: 1:25-100 WB: 1:200-1000. Researchers should empirically determine the suitability of the DLAT for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DLAT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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