Sodium Channel Voltage-Gated, Type III Beta Recombinant Protein | SCN3B recombinant protein
Recombinant Human Sodium Channel Voltage-Gated, Type III Beta, Sf9
Gene Names
SCN3B; SCNB3; ATFB16; BRGDA7; HSA243396
Purity
Greater than 95.0% as determined by SDS-PAGE
Synonyms
Sodium Channel Voltage-Gated; Type III Beta; Recombinant Human Sodium Channel Voltage-Gated; Sf9; Sodium channel subunit beta-3 precursor; Sodium channel; voltage-gated; type III; beta subunit; HSA243396; SCNB3; KIAA1158; SCN3B Human; Type III Beta Human Recombinant; SCN3B recombinant protein
Host
Sf9, Baculovirus cells
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE
Form/Format
Sterile filtered colorless solution
Protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol
Protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol
Sequence
ADP FPVCVEV PSETEAVQGN PMKLRCISCM KREEVEATTV VEWFYRPEGG KDFLIYEYRN GHQEVESPFQ GRLQWNGSKD LQDVSITVLN VTLNDSGLYT CNVSREFEFE AHRPFVKTTR LIPLRVTEEA GEDFTSVVSE HHHHHH
Sequence Length
215
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles
Related Product Information for SCN3B recombinant protein
Description: SCN3B Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 146 amino acids (23-159a.a.) and having a molecular mass of 16.8kDa (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). SCN3B is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Introduction: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. SCN3B is a part of the sodium channel beta subunit gene family whose members are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B influences the inactivation kinetics of the sodium channel.
Introduction: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. SCN3B is a part of the sodium channel beta subunit gene family whose members are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B influences the inactivation kinetics of the sodium channel.
Product Categories/Family for SCN3B recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
24,702 Da
NCBI Official Full Name
Sodium channel subunit beta-3
NCBI Official Synonym Full Names
sodium voltage-gated channel beta subunit 3
NCBI Official Symbol
SCN3B
NCBI Official Synonym Symbols
SCNB3; ATFB16; BRGDA7; HSA243396
NCBI Protein Information
sodium channel subunit beta-3
UniProt Protein Name
Sodium channel subunit beta-3
Protein Family
UniProt Gene Name
SCN3B
UniProt Synonym Gene Names
KIAA1158
NCBI Description
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons ().
Research Articles on SCN3B
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Product Notes
The SCN3B scn3b (Catalog #AAA147181) is a Recombinant Protein produced from Sf9, Baculovirus cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ADP FPVCVEV PSETEAVQGN PMKLRCISCM KREEVEATTV VEWFYRPEGG KDFLIYEYRN GHQEVESPFQ GRLQWNGSKD LQDVSITVLN VTLNDSGLYT CNVSREFEFE AHRPFVKTTR LIPLRVTEEA GEDFTSVVSE HHHHHH. It is sometimes possible for the material contained within the vial of "Sodium Channel Voltage-Gated, Type III Beta, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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