Serine/Threonine Kinase 17B Recombinant Protein | STK17B recombinant protein
Recombinant Human Serine/Threonine Kinase 17B
Gene Names
STK17B; DRAK2
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
Serine/Threonine Kinase 17B; Recombinant Human Serine/Threonine Kinase 17B; STK17B Human; Serine/Threonine Kinase 17B Human Recombinant; Serine/threonine-protein kinase 17B; EC 2.7.11.1; DAP kinase-related apoptosis-inducing protein kinase 2; STK17B; DRAK2; STK17B recombinant protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
STK17B protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 2mM DTT.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSRRRFD CRSISGLLTT TPQIPIKMEN FNNFYILTSK ELGRGKFAVV RQCISKSTGQ EYAAKFLKKR RRGQDCRAEI LHEIAVLELA KSCPRVINLH EVYENTSEII LILEYAAGGE IFSLCLPELA EMVSENDVIR LIKQILEGVY YLHQNNIVHLDLKPQNILLS SIYPLGDIKI VDFGMSRKIG HACELREIMG TPEYLAPEIL NYDPITTATD MWNIGIIAYM LLTHTSPFVG EDNQETYLNI SQVNVDYSEE TFSSVSQLAT DFIQSLLVKN PEKRPTAEIC LSHSWLQQWD FENLFHPEET SSSSQTQDHS VRSSEDKTSK SSCNGTCGDREDKENIPEDS SMVSKRFRFD DSLPNPHELV SDLLC.
Sequence Length
372
Related Product Information for STK17B recombinant protein
Description: STK17B Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 395 amino acids (1-372 a.a) and having a molecular mass of 44.7kDa.STK17B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Serine/threonine kinase 17b (STK17B) is a member of the protein kinase superfamily. STK17B functions as a positive regulator of apoptosis. STK17B interacts with CHP1; this interaction stimulates CHP1 to translocate from the Golgi to the nucleus. STK17B is highly expressed in the placenta, lung, pancreas, however it has lower levels in the heart, brain, liver, skeletal muscle and kidney.
Introduction: Serine/threonine kinase 17b (STK17B) is a member of the protein kinase superfamily. STK17B functions as a positive regulator of apoptosis. STK17B interacts with CHP1; this interaction stimulates CHP1 to translocate from the Golgi to the nucleus. STK17B is highly expressed in the placenta, lung, pancreas, however it has lower levels in the heart, brain, liver, skeletal muscle and kidney.
Product Categories/Family for STK17B recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,344 Da
NCBI Official Full Name
serine/threonine-protein kinase 17B
NCBI Official Synonym Full Names
serine/threonine kinase 17b
NCBI Official Symbol
STK17B
NCBI Official Synonym Symbols
DRAK2
NCBI Protein Information
serine/threonine-protein kinase 17B; DAP kinase-related apoptosis-inducing protein kinase 2; death-associated protein kinase-related 2
UniProt Protein Name
Serine/threonine-protein kinase 17B
Protein Family
UniProt Gene Name
STK17B
UniProt Synonym Gene Names
DRAK2
UniProt Entry Name
ST17B_HUMAN
Uniprot Description
DRAK2: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; EC 2.7.11.1; CAMK group; DAPK family
Chromosomal Location of Human Ortholog: 2q32.3
Cellular Component: ER-Golgi intermediate compartment; plasma membrane; nucleus; actin cytoskeleton
Molecular Function: protein serine/threonine kinase activity; ATP binding; protein kinase activity
Biological Process: apoptosis; protein amino acid autophosphorylation; protein amino acid phosphorylation
Research Articles on STK17B
Similar Products
Product Notes
The STK17B stk17b (Catalog #AAA145709) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMSR RRFD CRSISGLLTT TPQIPIKMEN FNNFYILTSK ELGRGKFAVV RQCISKSTGQ EYAAKFLKKR RRGQDCRAEI LHEIAVLELA KSCPRVINLH EVYENTSEII LILEYAAGGE IFSLCLPELA EMVSENDVIR LIKQILEGVY YLHQNNIVHL DLKPQNILLS SIYPLGDIKI VDFGMSRKIG HACELREIMG TPEYLAPEIL NYDPITTATD MWNIGIIAYM LLTHTSPFVG EDNQETYLNI SQVNVDYSEE TFSSVSQLAT DFIQSLLVKN PEKRPTAEIC LSHSWLQQWD FENLFHPEET SSSSQTQDHS VRSSEDKTSK SSCNGTCGDR EDKENIPEDS SMVSKRFRFD DSLPNPHELV SDLLC.. It is sometimes possible for the material contained within the vial of "Serine/Threonine Kinase 17B, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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