Small Nuclear Ribonucleoprotein Recombinant Protein | SNRPA1 recombinant protein
Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide A
Gene Names
SNRPA1; Lea1
Purity
Greater than 80% as determined by SDS-PAGE.
Synonyms
Small Nuclear Ribonucleoprotein; Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide A; SNRPA1 Human; Small Nuclear Ribonucleoprotein Polypeptide A Human Recombinant; U2 small nuclear ribonucleoprotein A'; U2 snRNP A'; SNRPA1; Lea1; SNRPA1 recombinant protein
Host
E Coli
Purity/Purification
Greater than 80% as determined by SDS-PAGE.
Form/Format
SNRPA1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 30% glycerol, 0.2M NaCl,2mM DTT and 0.1mM PMSF.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MVKLTAELIE QAAQYTNAVR DRELDLRGYK IPVIENLGAT LDQFDAIDFS DNEIRKLDGF PLLRRLKTLL VNNNRICRIG EGLDQALPCL TELILTNNSL VELGDLDPLA SLKSLTYLSI LRNPVTNKKH YRLYVIYKVP QVRVLDFQKV KLKERQEAEK MFKGKRGAQL AKDIARRSKT FNPGAGLPTD KKKGGPSPGD VEAIKNAIAN ASTLAEVERL KGLLQSGQIP GRERRSGPTD DGEEEMEEDT VTNGS
Sequence Length
255
Related Product Information for SNRPA1 recombinant protein
Description: SNRPA1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 275 amino acids (1-255 a.a.) and having a molecular mass of 30.5kDa. SNRPA1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: U2 small nuclear ribonucleoprotein A (SNRPA1), a 255 amino acid protein, is a component of the U2 snRNP which forms a complex with U2 snRNP B (U2B). U2 snRNP A and U2 snRNP B form together a complex which binds to the U2 snRNA hairpin IV. The configuration of the U2 snRNP A/U2 snRNP B dimer and the delicate variations of a few key residues regulate the snRNP-RNA-binding specificity.
Introduction: U2 small nuclear ribonucleoprotein A (SNRPA1), a 255 amino acid protein, is a component of the U2 snRNP which forms a complex with U2 snRNP B (U2B). U2 snRNP A and U2 snRNP B form together a complex which binds to the U2 snRNA hairpin IV. The configuration of the U2 snRNP A/U2 snRNP B dimer and the delicate variations of a few key residues regulate the snRNP-RNA-binding specificity.
Product Categories/Family for SNRPA1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,416 Da
NCBI Official Full Name
U2 small nuclear ribonucleoprotein A'
NCBI Official Synonym Full Names
small nuclear ribonucleoprotein polypeptide A'
NCBI Official Symbol
SNRPA1
NCBI Official Synonym Symbols
Lea1
NCBI Protein Information
U2 small nuclear ribonucleoprotein A'; U2 small nuclear ribonucleoprotein polypeptide A'; U2 snRNP A'
UniProt Protein Name
U2 small nuclear ribonucleoprotein A'
Protein Family
UniProt Gene Name
SNRPA1
UniProt Synonym Gene Names
U2 snRNP A'
UniProt Entry Name
RU2A_HUMAN
Uniprot Description
snRNP A': This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA. Belongs to the U2 small nuclear ribonucleoprotein A family.
Protein type: RNA-binding; RNA splicing; Spliceosome
Chromosomal Location of Human Ortholog: 15q26.3
Cellular Component: small nuclear ribonucleoprotein complex; nucleoplasm; spliceosome; snRNP U2
Molecular Function: protein binding
Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression
Research Articles on SNRPA1
Similar Products
Product Notes
The SNRPA1 snrpa1 (Catalog #AAA144403) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MVKLTAELIE QAAQYTNAVR DRELDLRGYK IPVIENLGAT LDQFDAIDFS DNEIRKLDGF PLLRRLKTLL VNNNRICRIG EGLDQALPCL TELILTNNSL VELGDLDPLA SLKSLTYLSI LRNPVTNKKH YRLYVIYKVP QVRVLDFQKV KLKERQEAEK MFKGKRGAQL AKDIARRSKT FNPGAGLPTD KKKGGPSPGD VEAIKNAIAN ASTLAEVERL KGLLQSGQIP GRERRSGPTD DGEEEMEEDT VTNGS. It is sometimes possible for the material contained within the vial of "Small Nuclear Ribonucleoprotein, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
