MIG Active Protein | rmMIG active protein
Recombinant Mouse MIG (CXCL9)
Gene Names
Cxcl9; CMK; Mig; MuMIG; Scyb9; crg-10; BB139920
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
MIG; Recombinant Mouse MIG (CXCL9); MIG Mouse; MIG Mouse Recombinant (CXCL9); Small inducible cytokine B9; CXCL9; Gamma interferon-induced monokine; chemokine (C-X-C motif) ligand 9; CMK; Humig; SCYB9; crg-10; M119; monokine induced by gamma-interferon; rmMIG active protein
Host
E Coli
Purity/Purification
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
The CXCL9 was lyophilized from a concentrated (1mg/ml) solution in water containing no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence
The sequence of the first five N-terminal amino acids was determined and was found to be, Thr-Leu-Val-Ile-Arg
Sequence Length
126
Solubility
It is recommended to reconstitute the lyophilized MIG in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
The Activity is calculated by the ability to chemoattract Human lymphocytes using a concentration of 0.1-1ng/ml corresponding to a Specific Activity of 1,000,000-10,000,000IU/mg.
Preparation and Storage
Lyophilized MIG although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CXCL9 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Related Product Information for rmMIG active protein
Description: MIG (monokine induced by gamma-interferon) Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 105 amino acids and having a molecular mass of 12208 Dalton. The MIG is purified by proprietary chromatographic techniques.
Introduction: Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by gamma interferon (MIG). CXCL9 is a T-cell chemoattractant, which is induced by IFN-?. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4. CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3.
Introduction: Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by gamma interferon (MIG). CXCL9 is a T-cell chemoattractant, which is induced by IFN-?. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4. CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3.
Product Categories/Family for rmMIG active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,444 Da
NCBI Official Full Name
C-X-C motif chemokine 9
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 9
NCBI Official Symbol
Cxcl9
NCBI Official Synonym Symbols
CMK; Mig; MuMIG; Scyb9; crg-10; BB139920
NCBI Protein Information
C-X-C motif chemokine 9; M119; gamma interferon-induced monokine; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma; protein m119; small inducible cytokine B subfamily (Cys-X-Cys), member 9; small-inducible cytokine B9
UniProt Protein Name
C-X-C motif chemokine 9
Protein Family
UniProt Gene Name
Cxcl9
UniProt Synonym Gene Names
Mig; Scyb9; MIG; MuMIG
UniProt Entry Name
CXCL9_MOUSE
Uniprot Description
CXCL9: Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Cellular Component: extracellular space; extracellular region; external side of plasma membrane
Molecular Function: CXCR3 chemokine receptor binding; chemokine activity; cytokine activity
Biological Process: G-protein coupled receptor protein signaling pathway; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; immune response; chemotaxis; inflammatory response; defense response to virus; positive regulation of myoblast differentiation; regulation of cell proliferation
Research Articles on rmMIG
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Product Notes
The rmMIG cxcl9 (Catalog #AAA142044) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: The sequence of the first five N-terminal amino acids was determined and was found to be, Thr-Leu-Va l-Ile-Arg. It is sometimes possible for the material contained within the vial of "MIG, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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