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Gamma-Synuclein Polyclonal Antibody | anti-SNCG antibody

Polyclonal Rabbit Anti Human Gamma-Synuclein

Gene Names
SNCG; SR; BCSG1
Applications
ELISA, Western Blot
Synonyms
Gamma-Synuclein; Polyclonal Antibody; Polyclonal Rabbit Anti Human Gamma-Synuclein; SNCG Antibody; Polyclonal Rabbit Anti-Human Antibody; Gamma-synuclein; Persyn; Breast cancer-specific gene 1 protein; Synoretin; SR; SNCG; BCSG1; PERSYN; PRSN; g-Synuclein; anti-SNCG antibody
Ordering
For Research Use Only!
Clonality
Polyclonal
Form/Format
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Sterile filtered colorless solution.
Sequence Length
127
Applicable Applications for anti-SNCG antibody
ELISA (EIA), Western Blot (WB)
Application Notes
gamma-Synuclein antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000.
Immunogen
Recombinant human gamma-Synuclein amino acids 1-127 purified from E Coli.
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
12 months at -20 degree C. 1 month at 4 degree C.
Related Product Information for anti-SNCG antibody
Introduction: gamma-synuclein (Originally known as a breast cancer specific gene product, BCSG1) is an acidic neuronal protein of 127 amino acids. Gamma-Synuclein is a member of the Synuclein protein family, which is believed to be involved in the pathogenesis of neurodegenerative diseases. High levels of Gamma-Synuclein have been found in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development. Synuclein-Gamma is found mostly in the peripheral nervous system (in primary sensory neurons, sympathetic neurons, and motor neurons) and retina. SNCG is also identified in the brain, ovarian tumors, and in the olfactory epithelium. SNCG expression in breast tumors is a marker for tumor progression. A modification in the expression of gamma-synuclein has been detected in the retina of Alzheimer''s patients.
Product Categories/Family for anti-SNCG antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
13,331 Da
NCBI Official Full Name
gamma-synuclein
NCBI Official Synonym Full Names
synuclein, gamma (breast cancer-specific protein 1)
NCBI Official Symbol
SNCG
NCBI Official Synonym Symbols
SR; BCSG1
NCBI Protein Information
gamma-synuclein; breast cancer-specific gene 1 protein; persyn; synoretin
UniProt Protein Name
Gamma-synuclein
Protein Family
UniProt Gene Name
SNCG
UniProt Synonym Gene Names
BCSG1; PERSYN; PRSN; SR
UniProt Entry Name
SYUG_HUMAN

NCBI Description

This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010]

Uniprot Description

SNCG: a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. May be involved in modulating axonal architecture during development and in the adult. Plays a role in neurofilament network integrity. High levels have been identified in advanced breast carcinomas.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 10q23.2-q23.3

Cellular Component: cell soma; perinuclear region of cytoplasm; cytoplasm; plasma membrane; microtubule organizing center; spindle; nerve terminal

Molecular Function: beta-tubulin binding; alpha-tubulin binding

Biological Process: response to drug; synaptic transmission; adult locomotory behavior; regulation of neurotransmitter secretion; synapse organization and biogenesis; protein secretion; response to cocaine; regulation of dopamine secretion

Research Articles on SNCG

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Product Notes

The SNCG sncg (Catalog #AAA141022) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Gamma-Synuclein can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). gamma-Synuclein antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000. Researchers should empirically determine the suitability of the SNCG sncg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Gamma-Synuclein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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